Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …
biomedical discoveries. It is also becoming increasingly important in industrial and medical …
Heating technology for malignant tumors: A review
The therapeutic application of heat is very effective in cancer treatment. Both hyperthermia,
ie, heating to 39–45° C to induce sensitization to radiotherapy and chemotherapy, and …
ie, heating to 39–45° C to induce sensitization to radiotherapy and chemotherapy, and …
First-in-human experience and acute procedural outcomes using a novel pulsed field ablation system: the PULSED AF pilot trial
Background: Pulsed field ablation (PFA) is a novel form of ablation using electrical fields to
ablate cardiac tissue. There are only limited data assessing the feasibility and safety of this …
ablate cardiac tissue. There are only limited data assessing the feasibility and safety of this …
Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer
Immunotherapy has only limited efficacy against pancreatic ductal adenocarcinoma (PDAC)
due to the presence of an immunosuppressive tumor-associated stroma. Here, we …
due to the presence of an immunosuppressive tumor-associated stroma. Here, we …
Irreversible electroporation: background, theory, and review of recent developments in clinical oncology
KN Aycock, RV Davalos - Bioelectricity, 2019 - liebertpub.com
Irreversible electroporation (IRE) has established a clinical niche as an alternative to thermal
ablation for the eradication of unresectable tumors, particularly those near critical vascular …
ablation for the eradication of unresectable tumors, particularly those near critical vascular …
A comprehensive review of calcium electroporation—A novel cancer treatment modality
SK Frandsen, M Vissing, J Gehl - Cancers, 2020 - mdpi.com
Calcium electroporation is a potential novel anti-cancer treatment where high calcium
concentrations are introduced into cells by electroporation, a method where short, high …
concentrations are introduced into cells by electroporation, a method where short, high …
Safety and chronic lesion characterization of pulsed field ablation in a Porcine model
Background Pulsed field ablation (PFA) has been identified as an alternative to thermal‐
based ablation systems for treatment of atrial fibrillation patients. The objective of this Good …
based ablation systems for treatment of atrial fibrillation patients. The objective of this Good …
Irreversible electroporation augments checkpoint immunotherapy in prostate cancer and promotes tumor antigen-specific tissue-resident memory CD8+ T cells
Memory CD8+ T cells populate non-lymphoid tissues (NLTs) following pathogen infection,
but little is known about the establishment of endogenous tumor-specific tissue-resident …
but little is known about the establishment of endogenous tumor-specific tissue-resident …
Irreversible electroporation: an emerging immunomodulatory therapy on solid tumors
N Zhang, Z Li, X Han, Z Zhu, Z Li, Y Zhao… - Frontiers in …, 2022 - frontiersin.org
Irreversible electroporation (IRE), a novel non-thermal ablation technique, is utilized to
ablate unresectable solid tumors and demonstrates favorable safety and efficacy in the …
ablate unresectable solid tumors and demonstrates favorable safety and efficacy in the …
[HTML][HTML] Engineering T cell response to cancer antigens by choice of focal therapeutic conditions
Focal thermal therapy (Heat), cryosurgery (Cryo) and irreversible electroporation (IRE) are
increasingly used to treat cancer. However, local recurrence and systemic spread are …
increasingly used to treat cancer. However, local recurrence and systemic spread are …