Heat shock proteins (Hsps) in cellular homeostasis: a promising tool for health management in crustacean aquaculture

V Kumar, S Roy, BK Behera, BK Das - Life, 2022 - mdpi.com
Heat shock proteins (Hsps) are a family of ubiquitously expressed stress proteins and
extrinsic chaperones that are required for viability and cell growth in all living organisms …

Barcoding heat shock proteins to human diseases: looking beyond the heat shock response

V Kakkar, M Meister-Broekema… - Disease models & …, 2014 - journals.biologists.com
There are numerous human diseases that are associated with protein misfolding and the
formation of toxic protein aggregates. Activating the heat shock response (HSR)–and thus …

Prolonged exposure to high fluoride levels during adolescence to adulthood elicits molecular, morphological, and functional impairments in the hippocampus

LO Bittencourt, A Dionizio, MKM Ferreira… - Scientific Reports, 2023 - nature.com
Fluoride is added to water due to its anticariogenic activity. However, due to its natural
presence in soils and reservoirs at high levels, it could be a potential environmental toxicant …

Proteomic approach underlying the hippocampal neurodegeneration caused by low doses of methylmercury after long-term exposure in adult rats

LO Bittencourt, A Dionizio, PC Nascimento, B Puty… - Metallomics, 2019 - academic.oup.com
Methylmercury (MeHg) is an important toxicant that causes cognitive dysfunctions in
humans. This study aimed to investigate the proteomic and biochemical alterations of the …

Extracellular heat shock proteins in cancer: From early diagnosis to new therapeutic approach

CC Bavisotto, AM Gammazza, C Campanella… - Seminars in Cancer …, 2022 - Elsevier
In cancer, human cells lose the ability to properly control the series of events that occur
constantly during cell growth and division, including protein expression, stability, and …

An overview on molecular chaperones enhancing solubility of expressed recombinant proteins with correct folding

M Mamipour, M Yousefi, M Hasanzadeh - International journal of biological …, 2017 - Elsevier
The majority of research topics declared that most of the recombinant proteins have been
expressed by Escherichia coli in basic investigations. But the majority of high expressed …

From molecules to behavior in long-term inorganic mercury intoxication: unraveling proteomic features in cerebellar neurodegeneration of rats

LO Bittencourt, VS Chemelo, WAB Aragão… - International Journal of …, 2021 - mdpi.com
Mercury is a severe environmental pollutant with neurotoxic effects, especially when
exposed for long periods. Although there are several evidences regarding mercury toxicity …

Reactive oxygen species generated by a heat shock protein (Hsp) inducing product contributes to Hsp70 production and Hsp70-mediated protective immunity in …

K Baruah, P Norouzitallab, L Linayati… - Developmental & …, 2014 - Elsevier
The cytoprotective role of heat shock protein (Hsp70) described in a variety of animal
disease models, including vibriosis in farmed aquatic animals, suggests that new protective …

[HTML][HTML] Protein-protein interaction network of celiac disease

MZ Azodi, H Peyvandi, M Rostami-Nejad… - … and Hepatology from …, 2016 - ncbi.nlm.nih.gov
Aim: The aim of this study is to investigate the Protein-Protein Interaction Network of Celiac
Disease. Background: Celiac disease (CD) is an autoimmune disease with susceptibility of …

Analysis of HSPA8 and HSPA9 mRNA Expression and Promoter Methylation in the Brain and Blood of Alzheimer's Disease Patients

PN Silva, TK Furuya, IL Braga… - Journal of …, 2013 - journals.sagepub.com
Alzheimer's disease (AD) is the most common form of dementia in elderly. Chaperones may
have a crucial role in AD due to their involvement in protein quality control, folding, and …