Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent causes of chronic liver
disease in the Western world, probably due to the growing prevalence of obesity, metabolic …

BACKGROUND It has long been thought that the factors affecting embryo and foetal
development were exclusively maternally derived; hence, if issues regarding fertility and …

A father's lifestyle impacts offspring health; yet, the underlying molecular mechanisms
remain elusive. We hypothesized that a diet that changes methyl donor availability will alter …

More than a century ago, August Weissman defined a distinction between the germline
(responsible for propagating heritable information from generation to generation) and the …

The type 2 diabetes epidemic and one of its predisposing factors, obesity, are major
influences on global health and economic burden. It is accepted that genetics and the …

Exposure to ubiquitous plastic-associated endocrine disrupting chemicals (EDCs) is
associated with the increased risk of many chronic diseases. For example, phthalate …

Maternal and paternal obesity and type 2 diabetes are recognized risk factors for the
development of metabolic dysfunction in offspring, even when the offspring follow a healthful …

Seminal fluid is often assumed to have just one function in mammalian reproduction,
delivering sperm to fertilize oocytes. But seminal fluid also transmits signaling agents that …

Background Infertility is a common reproductive disorder, with male factor infertility
accounting for approximately half of all cases. Taking a paternal perceptive, recent research …

Nutrition is a modifiable key factor that is able to interact with both the genome and
epigenome to influence human health and fertility. In particular, specific genetic variants can …