Most of the genetic variation associated with diabetes, through genome-wide association
studies, does not reside in protein-coding regions, making the identification of functional …

Selective estrogen receptor modulators (SERMs), used for the treatment of breast cancer,
osteoporosis, and menopausal symptoms, affect the nervous system. Some SERMs trigger …

Antioxidant activity has been attributed to the neuroprotective effects of Ginkgo biloba extract
EGb-761 on brain disorders including ischemic stroke. It is suggested that oxidative stress …

Aim Ginsenosides, a class of ginseng compounds of herbal medicine, have been shown to
have therapeutic potential for the neuroprotection of brain damage after cerebral ischemia …

Chronic exposure to manganese (Mn) causes neurotoxicity, referred to as manganism, with
common clinical features of parkinsonism. 17β-estradiol (E2) and tamoxifen (TX), a selective …

Radiation for medical use is a well-established therapeutic method with an excellent
prognosis rate for various cancer treatments. Unfortunately, a high dose of radiation therapy …

Estrogen has been implicated in the development and course of schizophrenia with most
evidence suggesting a neuroprotective effect. Treatment with raloxifene, a selective …

In our present investigation the neuroprotective effect of alcoholic extract of Hawthorn
(Crataegus oxycantha) was evaluated against middle cerebral artery occlusion induced …

Accumulating data from various clinical trial studies suggests that adjuvant therapy with
ovarian hormones (estrogens) could be effective in reducing cognitive deficit and …

Background: Modulatory effects of tamoxifen (TAM) on the central nervous system have
been reported. The effects of TAM on spatial and nonspatial learning and memory …