Enantioselective chemo‐and biocatalysis: partners in retrosynthesis

M Hönig, P Sondermann, NJ Turner… - Angewandte Chemie …, 2017 - Wiley Online Library
Recent developments of stereoselective biocatalytic and chemocatalytic methods are
discussed. The review provides a guide to the use of biocatalytic methods in the area of …

Biocatalytic asymmetric reduction of prochiral bulky-bulky ketones

AE Sardauna, M Abdulrasheed, A Nzila, MM Musa - Molecular Catalysis, 2023 - Elsevier
Biocatalytic asymmetric reduction of prochiral bulky-bulky ketones is an attractive approach
to produce their corresponding valuable enantiopure alcohols. These ketones contain alkyl …

Stereochemistry in asymmetric reduction of bulky–bulky ketones by alcohol dehydrogenases

J Zhou, G Xu, Y Ni - ACS Catalysis, 2020 - ACS Publications
Biocatalyzed asymmetric reduction of ketones is one of the most cost-effective and
environmentally friendly approaches for preparing chiral alcohols. However, few natural …

Oxidative dearomatization of indoles via Pd-catalyzed C–H oxygenation: An entry to C2-quaternary indolin-3-ones

SK Guchhait, V Chaudhary, VA Rana… - Organic …, 2016 - ACS Publications
An oxidative dearomatization chemistry of 2-arylindole via a unique pathway involving Pd-
catalyzed C–H peroxygenation is documented. Coupled with cascade transformation, it …

Alcohol Dehydrogenases with anti‐Prelog Stereopreference in Synthesis of Enantiopure Alcohols

MM Musa - ChemistryOpen, 2022 - Wiley Online Library
Biocatalytic production of both enantiomers of optically active alcohols with high
enantiopurities is of great interest in industry. Alcohol dehydrogenases (ADHs) represent an …

One‐Pot Asymmetric Oxidative Dearomatization of 2‐Substituted Indoles by Merging Transition Metal Catalysis with Organocatalysis to Access C2‐Tetrasubstituted …

YL Zhao, JX An, FF Yang, X Guan, XZ Fu… - Advanced Synthesis …, 2022 - Wiley Online Library
A one‐pot approach for the asymmetric synthesis of C2‐tetrasubstituted indolin‐3‐ones from
2‐substituted indoles was developed via merging transition metal catalysis with …

A cryptic pigment biosynthetic pathway uncovered by heterologous expression is essential for conidial development in Pestalotiopsis fici

P Zhang, X Wang, A Fan, Y Zheng, X Liu… - Molecular …, 2017 - Wiley Online Library
Spore pigmentation is very common in the fungal kingdom. The best studied pigment in
fungi is melanin which coats the surface of single cell spores. What and how pigments …

Tautomers of anthrahydroquinones: enzymatic reduction and implications for chrysophanol, monodictyphenone, and related xanthone biosyntheses

MA Schätzle, SM Husain, S Ferlaino… - Journal of the …, 2012 - ACS Publications
Reduction of emodin by sodium dithionite resulted in the formation of two tautomeric forms of
emodin hydroquinone. Subsequent conversion by the short-chain dehydrogenase …

Unprecedented role of hydronaphthoquinone tautomers in biosynthesis

SM Husain, MA Schätzle, S Lüdeke… - Angewandte …, 2014 - Wiley Online Library
Quinones and hydroquinones are among the most common cellular cofactors, redox
mediators, and natural products. Here, we report on the reduction of 2 …

Effects of Clostridium beijerinckii and Medium Modifications on Acetone–Butanol–Ethanol Production From Switchgrass

T Olorunsogbon, Y Adesanya, HK Atiyeh… - … in Bioengineering and …, 2022 - frontiersin.org
The presence of lignocellulose-derived microbial inhibitory compounds (LDMICs) in
lignocellulosic biomass (LB) hydrolysates is a barrier to efficient conversion of LB …