Glial and neuroimmune mechanisms as critical modulators of drug use and abuse

MJ Lacagnina, PD Rivera, SD Bilbo - Neuropsychopharmacology, 2017 - nature.com
Drugs of abuse cause persistent alterations in synaptic plasticity that may underlie addiction
behaviors. Evidence suggests glial cells have an essential and underappreciated role in the …

Neuroanatomical and neurophysiological mechanisms involved in central nervous system dysfunctions induced by prenatal alcohol exposure

C Guerri - Alcoholism: Clinical and Experimental Research, 1998 - Wiley Online Library
One of the most severe consequences of maternal ethanol consumption is the damage to
the developing central nervous system, which is manifested by long‐term cognitive and …

The Cell Wall-Associated Glyceraldehyde-3-Phosphate Dehydrogenase of Candida albicans Is Also a Fibronectin and Laminin Binding Protein

D Gozalbo, I Gil-Navarro, I Azorín… - Infection and …, 1998 - Am Soc Microbiol
By immunoelectron microscopy with a polyclonal antibody against the cytosolic glycolytic
enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from Candida albicans (anti …

Fetal alcohol spectrum disorders: an overview from the glia perspective

CJ Wilhelm, M Guizzetti - Frontiers in integrative neuroscience, 2016 - frontiersin.org
Alcohol consumption during pregnancy can produce a variety of central nervous system
(CNS) abnormalities in the offspring resulting in a broad spectrum of cognitive and …

Alcohol, astroglia, and brain development

C Guerri, J Renau-Piqueras - Molecular neurobiology, 1997 - Springer
Glial cells constitute one of the most common cell types in the brain. They play critical roles
in central nervous system (CNS) development. Recent evidence demonstrates that glial …

Molecular neuropathology of astrocytes and oligodendrocytes in alcohol use disorders

JJ Miguel-Hidalgo - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Postmortem studies reveal structural and molecular alterations of astrocytes and
oligodendrocytes in both the gray and white matter (GM and WM) of the prefrontal cortex …

LPS or ethanol triggers clathrin‐and rafts/caveolae‐dependent endocytosis of TLR 4 in cortical astrocytes

M Pascual‐Lucas, S Fernandez‐Lizarbe… - Journal of …, 2014 - Wiley Online Library
Abstract Toll‐like receptor 4 (TLR4) activation and signalling in glial cells play critical roles in
neurological disorders and in alcohol‐induced brain damage. TLR4 endocytosis upon …

Ceramide pathways modulate ethanol‐induced cell death in astrocytes

M Pascual, SL Valles… - Journal of …, 2003 - Wiley Online Library
We showed previously that alcohol exposure during in vivo brain development induced
astroglial damage and caused cell death. Because ceramide modulates a number of …

Alcohol exposure alters the expression pattern of neural cell adhesion molecules during brain development

R Minana, E Climent, D Barettino… - Journal of …, 2000 - Wiley Online Library
Neural cell adhesion molecules (NCAMs) play critical roles during development of the
nervous system. The aim of this study is to investigate the possible effect of ethanol …

The peptide NAP promotes neuronal growth and differentiation through extracellular signal‐regulated protein kinase and Akt pathways, and protects neurons co …

M Pascual, C Guerri - Journal of neurochemistry, 2007 - Wiley Online Library
We have previously shown that glial cells are a target of ethanol toxicity during brain
ontogeny, since ethanol affects glial development and impairs the release of neurotrophic …