Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to
the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular …

The control of steroidogenesis via signal transduction mechanisms involving cAMP-
dependent and cAMP-independent mechanisms is reviewed. Several structurally unrelated …

The metabolism of cholesterol by cytochrome P450 side chain cleavage enzyme is
hormonally regulated in steroidogenic tissues via intramitochondrial cholesterol transport …

This study was conducted to examine the mechanism for arachidonic acid (AA) regulation of
steroidogenic acute regulatory (StAR) protein expression and the relationship between AA …

The age-related decline in testosterone biosynthesis in testicular Leydig cells has been well
documented, but the mechanisms involved in the decline are not clear. Recent studies have …

Long chain acyl-CoA esters are important intermediates in degradation and synthesis of fatty
acids, as well as having important functions in regulation of intermediary metabolism and …

We hypothesized that certain proteins encoded by temperature-responsive genes in brown
adipose tissue (BAT) contribute to the remarkable metabolic shifts observed in this tissue …

Acyl-CoA thioesterases, also known as acyl-CoA hydrolases, are a group of enzymes that
hydrolyze CoA esters such as acyl-CoAs (saturated, unsaturated, branched-chain), bile acid …

Arachidonic acid and its lypoxygenated metabolites play a fundamental role in the hormonal
regulation of steroidogenesis. Reduction in the expression of the mitochondrial acyl‐CoA …

The decline in blood testosterone concentration during the course of male aging results in
decreases in many physiological functions. However, the mechanism (s) responsible for this …