Multifunctional intracellular matrix metalloproteinases: implications in disease
Matrix metalloproteinases (MMPs) are zinc‐dependent endopeptidases that were first
discovered as proteases, which target and cleave extracellular proteins. During the past 20 …
discovered as proteases, which target and cleave extracellular proteins. During the past 20 …
Biochemical and biological attributes of matrix metalloproteinases
N Cui, M Hu, RA Khalil - Progress in molecular biology and translational …, 2017 - Elsevier
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that are
involved in the degradation of various proteins in the extracellular matrix (ECM). Typically …
involved in the degradation of various proteins in the extracellular matrix (ECM). Typically …
Matrix metalloproteinases, vascular remodeling, and vascular disease
X Wang, RA Khalil - Advances in pharmacology, 2018 - Elsevier
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that
degrade various proteins in the extracellular matrix (ECM). Typically, MMPs have a …
degrade various proteins in the extracellular matrix (ECM). Typically, MMPs have a …
Matrix metalloproteinases and their inhibitors in pulmonary fibrosis: EMMPRIN/CD147 comes into play
L Chuliá-Peris, C Carreres-Rey, M Gabasa… - International journal of …, 2022 - mdpi.com
Pulmonary fibrosis (PF) is characterized by aberrant extracellular matrix (ECM) deposition,
activation of fibroblasts to myofibroblasts and parenchymal disorganization, which have an …
activation of fibroblasts to myofibroblasts and parenchymal disorganization, which have an …
Physiology and pathophysiology of matrix metalloproteases
T Klein, R Bischoff - Amino acids, 2011 - Springer
Matrix metalloproteases (MMPs) comprise a family of enzymes that cleave protein substrates
based on a conserved mechanism involving activation of an active site-bound water …
based on a conserved mechanism involving activation of an active site-bound water …
Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry
R Visse, H Nagase - Circulation research, 2003 - Am Heart Assoc
Matrix metalloproteinases (MMPs), also designated matrixins, hydrolyze components of the
extracellular matrix. These proteinases play a central role in many biological processes …
extracellular matrix. These proteinases play a central role in many biological processes …
MMPs in learning and memory and neuropsychiatric disorders
Matrix metalloproteinases (MMPs) are a group of over twenty proteases, operating chiefly
extracellularly to cleave components of the extracellular matrix, cell adhesion molecules as …
extracellularly to cleave components of the extracellular matrix, cell adhesion molecules as …
Structure and function of matrix metalloproteinases and TIMPs
H Nagase, R Visse, G Murphy - Cardiovascular research, 2006 - academic.oup.com
Matrix metalloproteinases (MMPs), also called matrixins, function in the extracellular
environment of cells and degrade both matrix and non-matrix proteins. They play central …
environment of cells and degrade both matrix and non-matrix proteins. They play central …
Matrix metalloproteinases
H Nagase - Zinc metalloproteases in health and disease, 1996 - taylorfrancis.com
Matrix metalloproteinases (MMPs), also designated matnxms, are a family of related zinc
metalloendopeptidases that function in the turnover of components of the extracellular …
metalloendopeptidases that function in the turnover of components of the extracellular …
How matrix metalloproteinases regulate cell behavior
MD Sternlicht, Z Werb - Annual review of cell and …, 2001 - annualreviews.org
▪ Abstract The matrix metalloproteinases (MMPs) constitute a multigene family of over 25
secreted and cell surface enzymes that process or degrade numerous pericellular …
secreted and cell surface enzymes that process or degrade numerous pericellular …