Substituted 2-anilinopyrimidines useful as protein kinase inhibitors
PD Davis, DFC Moffat, JM Davis… - US Patent …, 2001 - Google Patents
Kroon, AP et al.,“SN (ANRORC)[addition nucleophilic ring opening—ring closing]—
mechanism. XIII. SN (AN RORC) mechanism in the amination of 2—substituted 4—phe …
mechanism. XIII. SN (AN RORC) mechanism in the amination of 2—substituted 4—phe …
5-cyano-2-aminopyrimidine derivatives
MJ Batchelor, DFC Moffat, JM Davis… - US Patent …, 2003 - Google Patents
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12/1988 EP O 337 943 A2 10/1989 EP O 393 500 A1 10/1990 EP O 490,823 A1 6/1991 EP …
Pyrazole compositions useful as inhibitors of ERK
M Hale, J Janetka, F Maltais, J Cao - US Patent 6,784,195, 2004 - Google Patents
The present invention is in the field of medicinal chem istry and relates to pyrazole
compounds that are protein kinase inhibitors, especially inhibitors of ERK, composi tions …
compounds that are protein kinase inhibitors, especially inhibitors of ERK, composi tions …
Pyrazole compositions useful as inhibitors of ERK
M Hale, X Xie, J Green, J Cao, C Baker… - US Patent …, 2003 - Google Patents
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vinylpyrroles”, Heterocycles, 14 (2): MA (US) ss 185-188, 1980 (see in particular p. 186 …
Compound and a composition including such a compound
T Brumby, R Jautelat, O Prien, M Schäfer… - US Patent …, 2007 - Google Patents
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Gazave et al. 4,153,713 A 5, 1979 Huth et al. 4,193.926 A 3, 1980 Schmiechen et al …
Substituted 2-anilinopyrimidines useful as protein kinase inhibitors
MC Hutchings, PD Davis, DFC Moffat - US Patent 6,337,335, 2002 - Google Patents
DE 2SO 1443 7/1975 DE 34 36 380 A1 4/1986 EP O 233 461 A2 8/1987 EP O 295 21.0 A1
12/1988 EP O 337 943 A2 10/1989 EP O 393 500 A1 10/1990 EP O 490,823 A1 6/1991 EP …
12/1988 EP O 337 943 A2 10/1989 EP O 393 500 A1 10/1990 EP O 490,823 A1 6/1991 EP …
2-pyrimidineamine derivatives and processes for their preparation
PD Davis, DFC Moffat, MJ Batchelor… - US Patent …, 2003 - Google Patents
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932 2 313 422 2545.356 A1 1588639 61-112059 3-77872 3-77923 WO 87/06576 WO …
932 2 313 422 2545.356 A1 1588639 61-112059 3-77872 3-77923 WO 87/06576 WO …
Pyrazole compositions useful as inhibitors of ERK
J Green, J Cao, M Hale, C Baker, F Maltais… - US Patent …, 2003 - Google Patents
This application is a divisional of US patent application Ser. No. 09/972.437, now US Pat.
No. 6,528,509 filed Oct. 5, 2001, which is a continuation of and claims priority to International …
No. 6,528,509 filed Oct. 5, 2001, which is a continuation of and claims priority to International …
Pyrazole compositions useful as inhibitors of ERK
M Hale, J Janetka, F Maltais - US Patent 6,949,580, 2005 - Google Patents
The present invention is in the field of medicinal chem istry and relates to pyrazole
compounds that are protein kinase inhibitors, especially inhibitors of ERK, composi tions …
compounds that are protein kinase inhibitors, especially inhibitors of ERK, composi tions …
Pyrazole compositions useful as inhibitors of erk
M Hale, X Xie, J Green, J Cao, C Baker… - US Patent …, 2006 - Google Patents
Described herein are compounds that are useful as protein kinase inhibitors having the
formula: where R'', Q, and T are described in the specification. The compounds are useful for …
formula: where R'', Q, and T are described in the specification. The compounds are useful for …