Recent thymic emigrants (RTEs) are naïve T cells that egress the thymus following
intrathymic development. This continuous process, including self-renewal, is crucial to …

The thymus gland is a primary lymphoid organ for T-cell development. Various viral
infections can result in disturbance of thymic functions. Medullary thymic epithelial cells …

Background CD4+ recent thymic emigrants (CD4+ RTEs) constitute a subset of T cells
recently generated in the thymus and exported into peripheral blood. CD4+ RTEs have …

We performed a case-series analysis of reactivation of herpesvirus in patients with hepatitis
C virus (HCV) infection treated with direct-acting antiviral (DAA) agents. We collected data …

The factors involved in thymus regeneration after chemotherapy has not been sufficiently
explored. This study was aimed to identify the clinical characteristics and single-nucleotide …

Objective: The effects of hepatitis C virus (HCV) coinfection on immune homeostasis and
immune restoration in treated HIV infection are not well understood. Methods: We studied 79 …

Background Injecting drug users (IDU) are at premature risk of developing multimorbidity
and mortality from causes commonly observed in the elderly. Ageing of the immune system …

Abstract The Bacillus Calmette–Guérin vaccine (BCG) has been associated with beneficial
non-specific effects (NSEs) on infant health. Within a randomized trial on the effect of …

Generalized CD8+ T-cell impairment in chronic hepatitis C virus (HCV) infection and the
contribution of liver-infiltrating CD8+ T-cells to the immunopathogenesis of this infection …

Background The mechanisms underlying naïve CD4+ lymphopenia during chronic Hepatitis
C Virus (HCV) infection are unclear. Whether direct-acting antiviral (DAA) therapy restores …