[HTML][HTML] Causes and consequences of snake venom variation
Snake venoms are mixtures of toxins that vary extensively between and within snake
species. This variability has serious consequences for the management of the world's 1.8 …
species. This variability has serious consequences for the management of the world's 1.8 …
[HTML][HTML] Multifunctional toxins in snake venoms and therapeutic implications: from pain to hemorrhage and necrosis
Animal venoms have evolved over millions of years for prey capture and defense from
predators and rivals. Snake venoms, in particular, have evolved a wide diversity of peptides …
predators and rivals. Snake venoms, in particular, have evolved a wide diversity of peptides …
The rise of genomics in snake venom research: recent advances and future perspectives
Snake venoms represent a danger to human health, but also a gold mine of bioactive
proteins that can be harnessed for drug discovery purposes. The evolution of snakes and …
proteins that can be harnessed for drug discovery purposes. The evolution of snakes and …
[HTML][HTML] The rise and fall of an evolutionary innovation: contrasting strategies of venom evolution in ancient and young animals
Animal venoms are theorized to evolve under the significant influence of positive Darwinian
selection in a chemical arms race scenario, where the evolution of venom resistance in prey …
selection in a chemical arms race scenario, where the evolution of venom resistance in prey …
Intraspecific venom variation in the medically significant Southern Pacific Rattlesnake (Crotalus oreganus helleri): biodiscovery, clinical and evolutionary implications
Due to the extreme variation of venom, which consequently results in drastically variable
degrees of neutralization by CroFab antivenom, the management and treatment of …
degrees of neutralization by CroFab antivenom, the management and treatment of …
[HTML][HTML] Three-fingered RAVERs: Rapid Accumulation of Variations in Exposed Residues of snake venom toxins
Three-finger toxins (3FTx) represent one of the most abundantly secreted and potently toxic
components of colubrid (Colubridae), elapid (Elapidae) and psammophid (Psammophiinae …
components of colubrid (Colubridae), elapid (Elapidae) and psammophid (Psammophiinae …
Adaptive evolution of distinct prey-specific toxin genes in rear-fanged snake venom
Venom proteins evolve rapidly, and as a trophic adaptation are excellent models for
predator–prey evolutionary studies. The key to a deeper understanding of venom evolution …
predator–prey evolutionary studies. The key to a deeper understanding of venom evolution …
[HTML][HTML] Snake venom in context: neglected clades and concepts
TNW Jackson, H Jouanne, N Vidal - Frontiers in Ecology and …, 2019 - frontiersin.org
Despite the fact that venom is an intrinsically ecological trait, the ecological perspective has
been widely neglected in toxinological research. This neglect has hindered our …
been widely neglected in toxinological research. This neglect has hindered our …
[HTML][HTML] Dynamic genetic differentiation drives the widespread structural and functional convergent evolution of snake venom proteinaceous toxins
Background The explosive radiation and diversification of the advanced snakes (superfamily
Colubroidea) was associated with changes in all aspects of the shared venom system …
Colubroidea) was associated with changes in all aspects of the shared venom system …
Expression of venom gene homologs in diverse python tissues suggests a new model for the evolution of snake venom
J Reyes-Velasco, DC Card, AL Andrew… - Molecular biology …, 2015 - academic.oup.com
Snake venom gene evolution has been studied intensively over the past several decades,
yet most previous studies have lacked the context of complete snake genomes and the full …
yet most previous studies have lacked the context of complete snake genomes and the full …