[HTML][HTML] The groovy TMEM16 family: molecular mechanisms of lipid scrambling and ion conduction
V Kalienkova, VC Mosina, C Paulino - Journal of Molecular Biology, 2021 - Elsevier
The TMEM16 family of membrane proteins displays a remarkable functional dichotomy–
while some family members function as Ca 2+-activated anion channels, the majority of …
while some family members function as Ca 2+-activated anion channels, the majority of …
Known structures and unknown mechanisms of TMEM16 scramblases and channels
The TMEM16 family of membrane proteins is composed of both Ca2+-gated Cl− channels
and Ca2+-dependent phospholipid scramblases. The functional diversity of TMEM16s …
and Ca2+-dependent phospholipid scramblases. The functional diversity of TMEM16s …
Evidence of novel susceptibility variants for prostate cancer and a multiancestry polygenic risk score associated with aggressive disease in men of African ancestry
Background Genetic factors play an important role in prostate cancer (PCa) susceptibility.
Objective To discover common genetic variants contributing to the risk of PCa in men of …
Objective To discover common genetic variants contributing to the risk of PCa in men of …
Co-expression of cancer stem cell markers OCT4 and NANOG predicts poor prognosis in renal cell carcinomas
Many renal cancer patients experience disease recurrence after combined treatments or
immunotherapy due to permanence of cancer stem cells (CSCs). This study was conducted …
immunotherapy due to permanence of cancer stem cells (CSCs). This study was conducted …
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans
A Amin Al Olama, T Dadaev, DJ Hazelett… - Human molecular …, 2015 - academic.oup.com
Genome-wide association studies (GWAS) have identified numerous common prostate
cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the …
cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the …
3D protein-based bilayer artificial skin for the guided scarless healing of third-degree burn wounds in vivo
M Gholipourmalekabadi, AM Seifalian… - …, 2018 - ACS Publications
Severe burn injuries can lead to delays in healing and devastating scar formation. Attempts
have been made to develop a suitable skin substitute for the scarless healing of such skin …
have been made to develop a suitable skin substitute for the scarless healing of such skin …
Differential expression of cancer stem cell markers ALDH1 and CD133 in various lung cancer subtypes
Cancer stem cells (CSCs) are hypothesized to be the main culprit of lung cancer
progression. Clinicopathological significance of stem cell markers CD133 and ALDH1 in a …
progression. Clinicopathological significance of stem cell markers CD133 and ALDH1 in a …
CD44 epithelial isoform inversely associates with invasive characteristics of colorectal cancer
Aim: There is no consensus regarding the clinical significance of CD44 and CD24 as cancer
stem cell (CSC) marker in colorectal cancer (CRC). Methodology: A total of 494 CRC …
stem cell (CSC) marker in colorectal cancer (CRC). Methodology: A total of 494 CRC …
ALDH1 in combination with CD44 as putative cancer stem cell markers are correlated with poor prognosis in urothelial carcinoma of the urinary bladder
H Keymoosi, E Gheytanchi, M Asgari… - Asian Pacific Journal …, 2014 - koreascience.kr
Background: The aldehyde dehydrogenase 1 family member A1 (ALDH1A1) is one of the
promising markers for identifying cancer stem cells in many cancer types, along with other …
promising markers for identifying cancer stem cells in many cancer types, along with other …
ANO7 is associated with aggressive prostate cancer
E Kaikkonen, T Rantapero, Q Zhang… - … journal of cancer, 2018 - Wiley Online Library
Prostate cancer is one of the most common and heritable human cancers. Our aim was to
find germline biomarkers that can predict disease outcome. We previously detected …
find germline biomarkers that can predict disease outcome. We previously detected …