Diabetes mellitus and osteoporosis correlation: challenges and hopes

M Ala, RM Jafari, AR Dehpour - Current Diabetes Reviews, 2020 - ingentaconnect.com
Diabetes and osteoporosis are two common diseases with different complications. Despite
different therapeutic strategies, managing these diseases and reducing their burden have …

Medium-intensity treadmill exercise exerts beneficial effects on bone modeling through bone marrow mesenchymal stromal cells

L Zhang, Y Yuan, W Wu, Z Sun, L Lei, J Fan… - Frontiers in Cell and …, 2020 - frontiersin.org
As a type of multipotential cells, bone marrow mesenchymal stromal cells (BMMSCs) can
differentiate into chondrocytes, osteoblasts, and adipocytes under different loading condition …

MicroRNA-101a enhances trabecular bone accrual in male mice

A Dudakovic, S Jerez, PJ Deosthale, JM Denbeigh… - Scientific reports, 2022 - nature.com
High-throughput microRNA sequencing was performed during differentiation of MC3T3-E1
osteoblasts to develop working hypotheses for specific microRNAs that control …

Mefloquine improves pulmonary fibrosis by inhibiting the KCNH2/Jak2/Stat3 signaling pathway in macrophages

J Zhou, X Yang, Y Liu, J Guo, Z Liu, Y Li, Y Bai… - Biomedicine & …, 2024 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a life-threatening disease characterized by severe
pulmonary fibrosis, for which there is an urgent need for effective therapeutic agents …

Combination mode of antimalarial drug mefloquine and human serum albumin: Insights from spectroscopic and docking approaches

KA Musa, NFW Ridzwan, SB Mohamad… - Biopolymers, 2020 - Wiley Online Library
The interaction between mefloquine (MEF), the antimalarial drug, and human serum
albumin (HSA), the main carrier protein in blood circulation, was explored using …

[HTML][HTML] Sex-specific differences in direct osteoclastic versus indirect osteoblastic effects underlay the low bone mass of Pannexin1 deletion in TRAP-expressing cells …

P Deosthale, JM Hong, AL Essex, W Rodriguez… - Bone Reports, 2022 - Elsevier
Abstract Pannexin1 (Panx1) is a hemichannel-forming protein that participates in the
communication of cells with the extracellular space. To characterize the role of osteoclastic …

In vitro and in vivo studies using non-traditional bisphosphonates

LI Plotkin, S Buvinic, J Balanta-Melo - Bone, 2020 - Elsevier
Non-traditional bisphosphonates, that is, bisphosphonates that do not inhibit osteoclast
viability or function, were initially reported in the 1990s by Socrates Papapoulos' group …

MicroRNA regulation in osteocytes

LI Plotkin, HM Davis - Current Molecular Biology Reports, 2018 - Springer
Abstract Purpose of Review The role of microRNA (miR) regulation during the processes of
bone homeostasis and remodeling has been a key research topic in recent years. Extensive …

Response to RL Nevin" Considerations in the repurposing of mefloquine for prevention and treatment of osteoporosis"

HM Davis, R Pacheco-Costa, LI Plotkin - Bone, 2018 - pubmed.ncbi.nlm.nih.gov
Response to RL Nevin "Considerations in the repurposing of mefloquine for prevention and
treatment of osteoporosis" Response to RL Nevin "Considerations in the repurposing of …

[引用][C] Considerations in the repurposing of mefloquine for prevention and treatment of osteoporosis.

RL Nevin - Bone, 2018 - europepmc.org
This is a comment on" Reversal of loss of bone mass in old mice treated with mefloquine."
Bone. 2018 Sep; 114: 22-31. A comment on this article appears in" Response to RL Nevin" …