A fundamental step of tumor metastasis is tumor cell migration away from the primary tumor
site. One mode of migration that is essential but still understudied is collective invasion, the …

Collective cell migration, where cells move as a cohesive unit, is a vital process underlying
morphogenesis and cancer metastasis. Thanks to recent advances in imaging and …

Herein, we report a series of new octahedral iridium (III) complexes Ir1–Ir9 of the type [Ir (N^
N^ N)(C^ N) Cl] PF6 (N^ N^ N= 4′-(p-tolyl)-2, 2′: 6′, 2 ″-terpyridine; C^ N …

Phenotypic heterogeneity poses a significant hurdle for cancer treatment but is under-
characterized in the context of tumor invasion. Amidst the range of phenotypic heterogeneity …

Background Conjugation of transferrin (Tf) to imaging or nanotherapeutic agents is a
promising strategy to target breast cancer. Since the efficacy of these biomaterials often …

Cancer is a highly heterogeneous disease, and thus treatment responses vary greatly
between patients. To improve therapy efficacy and outcome for cancer patients, more …

Bladder cancer (BC) is featured as the second most common malignancy of the urinary tract
worldwide with few treatments leading to high incidence and mortality. It stayed a virtually …

Breast cancer is well known for its significant heterogeneity, and numerous studies have
focused primarily on intertumor heterogeneity. However, increasing evidence highlights the …

Objective As a dominant component within the tumor microenvironment, macrophages exert
an essential role in almost all aspects of triple-negative breast cancer (TNBC). This work …