The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

The last decade has witnessed enormous research focused on cationic polymers. Cationic
polymers are the subject of intense research as non-viral gene delivery systems, due to their …

Polyethylenimine (PEI) has recently been widely studied for the design of nucleic acid
delivery vehicles. Gene delivery using PEI involves condensation of DNA into compact …

Silanes are widely used to enhance the corrosion resistance of cement-based materials by
endowing the substrate with hydrophobicity. However, their applications in fly ash/slag …

Polymer carriers like PEI which proved their efficiency in DNA delivery were found to be far
less effective for the applications with siRNA. In the current study, we generated a number of …

Conspectus The field of gene therapy, which aims to treat patients by modulating gene
expression, has come to fruition and has landed several landmark FDA approvals. Most …

Phosphate originated from industrial effluents is one of the key factors responsible for
eutrophication of the receiving waterways especially in the developing countries such as …

Figure S2. A) DNA polyplex stability in serum determined by agarose gel shift assay at N/P
ratio of 16 and different FBS serum concentrations. DNA polyplex formation (in 20 mM …

Cellular delivery of biomacromolecules is vital to medical research and therapeutic
development. Cationic polymers are promising and affordable candidate vehicles for these …

Herein, a novel series of multivalent polycationic β-cyclodextrin “click clusters” with discrete
molecular weight have been synthesized, characterized, and examined as therapeutic …