Structure and function of ion channels regulating sperm motility—an overview

K Nowicka-Bauer, M Szymczak-Cendlak - International journal of …, 2021 - mdpi.com
Sperm motility is linked to the activation of signaling pathways that trigger movement. These
pathways are mainly dependent on Ca2+, which acts as a secondary messenger. The …

A review on the role of bicarbonate and proton transporters during sperm capacitation in mammals

A Delgado-Bermúdez, M Yeste, S Bonet… - International Journal of …, 2022 - mdpi.com
Alkalinization of sperm cytosol is essential for plasma membrane hyperpolarization,
hyperactivation of motility, and acrosomal exocytosis during sperm capacitation in mammals …

Zinc is a master-regulator of sperm function associated with binding, motility, and metabolic modulation during porcine sperm capacitation

M Zigo, K Kerns, S Sen, C Essien, R Oko, D Xu… - Communications …, 2022 - nature.com
Sperm capacitation is a post-testicular maturation step endowing spermatozoa with
fertilizing capacity within the female reproductive tract, significant for fertility, reproductive …

Blocking NHE channels reduces the ability of in vitro capacitated mammalian sperm to respond to progesterone stimulus

M Yeste, S Recuero, C Maside, A Salas-Huetos… - International Journal of …, 2021 - mdpi.com
Few data exist about the presence and physiological role of Na+/H+ exchangers (NHEs) in
the plasma membrane of mammalian sperm. In addition, the involvement of these channels …

Introduction to the pathways involved in the activation and regulation of sperm motility: A review of the relevance of ion channels

DK Swain, P Sharma, N Shah, M Sethi… - Animal reproduction …, 2022 - Elsevier
To participate in sperm–oocyte fusion, spermatozoa need to be motile. In the testes,
spermatozoa are immotile, although these gametes acquire the capacity for motility during …

HVCN1 channels are relevant for the maintenance of sperm motility during in vitro capacitation of pig spermatozoa

M Yeste, M Llavanera, Y Mateo-Otero… - International journal of …, 2020 - mdpi.com
The objective of the present study was to determine the physiological role of voltage-gated
hydrogen channels 1 (HVCN1 channels) during in vitro capacitation of pig spermatozoa …

Interplay mechanisms between progesterone and endocannabinoid receptors in regulating bull sperm capacitation and acrosome reaction

A Mahajan, P Sharma, AK Mishra… - Journal of Cellular …, 2022 - Wiley Online Library
After ejaculation, sperm show a limited capacity for transcription and translation. In the
oviduct, most of the signalling in sperm is nongenomic and is mediated through membrane …

Signaling roleplay between ion channels during mammalian sperm capacitation

F Benko, D Urminská, M Ďuračka, E Tvrdá - Biomedicines, 2023 - mdpi.com
In order to accomplish their primary goal, mammalian spermatozoa must undergo a series of
physiological, biochemical, and functional changes crucial for the acquisition of fertilization …

Effects of diluent pH on enrichment and performance of dairy goat X/Y sperm

Q He, S Wu, M Huang, Y Wang, K Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
In this paper, on the basis of the differences in the hydrogen ion concentration (pH) of the
diluent dairy goat semen on X/Y sperm motility, an X/Y sperm enrichment study was …

Diluent pH affects sperm motility via GSK3 α/β-hexokinase pathway for the efficient enrichment of X-sperm to increase the female kids rate of dairy goats

Q He, S Wu, F Gao, X Xu, S Wang, Z Xu, M Huang… - Theriogenology, 2023 - Elsevier
Dairy goats are the goats bred with the ability to produce large quantities of milk, and the
increase of the female kid rate of breeding dairy goats is beneficial for milk production and …