Design, clinical translation and immunological response of biomaterials in regenerative medicine

K Sadtler, A Singh, MT Wolf, X Wang… - Nature Reviews …, 2016 - nature.com
The field of regenerative medicine aims to replace tissues lost as a consequence of disease,
trauma or congenital abnormalities. Biomaterials serve as scaffolds for regenerative …

Designing biomaterials with immunomodulatory properties for tissue engineering and regenerative medicine

JI Andorko, CM Jewell - Bioengineering & translational …, 2017 - Wiley Online Library
Recent research in the vaccine and immunotherapy fields has revealed that biomaterials
have the ability to activate immune pathways, even in the absence of other immune …

Improving vaccine and immunotherapy design using biomaterials

ML Bookstaver, SJ Tsai, JS Bromberg, CM Jewell - Trends in immunology, 2018 - cell.com
Polymers, lipids, scaffolds, microneedles, and other biomaterials are rapidly emerging as
technologies to improve the efficacy of vaccines against infectious disease and …

Current advances in the development of novel polymeric nanoparticles for the treatment of neurodegenerative diseases

A Cano, E Sánchez-López, M Ettcheto… - …, 2020 - Future Medicine
Effective intervention is essential to combat the coming epidemic of neurodegenerative (ND)
diseases. Nanomedicine can overcome restrictions of CNS delivery imposed by the blood …

[PDF][PDF] Reprogramming the local lymph node microenvironment promotes tolerance that is systemic and antigen specific

LH Tostanoski, YC Chiu, JM Gammon, T Simon… - Cell reports, 2016 - cell.com
Many experimental therapies for autoimmune diseases, such as multiple sclerosis (MS), aim
to bias T cells toward tolerogenic phenotypes without broad suppression. However, the link …

RSM-CCD design of malachite green adsorption onto activated carbon with multimodal pore size distribution prepared from Amygdalus scoparia: Kinetic and isotherm …

R Bagheri, M Ghaedi, A Asfaram, EA Dil, H Javadian - Polyhedron, 2019 - Elsevier
In the present work, the activated carbon (AC) adsorbent with multimodal pore size
distribution prepared from Amygdalus scoparia as low-cost and locally available source was …

Exploiting PLGA-based biocompatible nanoparticles for next-generation tolerogenic vaccines against autoimmune disease

G Cappellano, C Comi, A Chiocchetti… - International Journal of …, 2019 - mdpi.com
Tolerogenic vaccines are aimed at inhibiting antigen-specific immune responses. Antigen-
loaded nanoparticles (NPs) have been recently emerged as ideal tools for tolerogenic …

Biocompatibility of biomaterials for nanoencapsulation: Current approaches

BA Witika, PA Makoni, SK Matafwali, B Chabalenge… - Nanomaterials, 2020 - mdpi.com
Nanoencapsulation is an approach to circumvent shortcomings such as reduced
bioavailability, undesirable side effects, frequent dosing and unpleasant organoleptic …

Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment

Y Huang, X Guo, Y Wu, X Chen, L Feng, N Xie… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

Engineering immunological tolerance using quantum dots to tune the density of self‐antigen display

KL Hess, E Oh, LH Tostanoski… - Advanced functional …, 2017 - Wiley Online Library
Treatments for autoimmunity—diseases where the immune system mistakenly attacks self‐
molecules—are not curative and leave patients immunocompromised. New studies aimed at …