This article reviews the dynamic interactions of the tumour microenvironment, highlighting
the roles of acetyl-CoA and melatonergic pathway regulation in determining the interactions …

There is an under-recognized role of the aryl hydrocarbon receptor (AhR) in co-ordinating
the entry and pathophysiology of the severe acute respiratory syndrome-coronavirus-2 …

The aryl hydrocarbon receptor was previously known as an environmental receptor that
modulates the cellular response to external environmental changes. In essence, the aryl …

Background The unmet needs in treating acute myeloid leukemia (AML) promote us to look
for more effective and less toxic therapies. In this study, we discovered that Yinzhihuang …

Parkinson's disease (PD) is a disease of an unknown origin. Despite that, decades of
research have provided considerable evidence that alpha-synuclein (αSyn) is central to the …

Background Prolonged inflammation, oxidative stress, and protein aggregation are
important factors contributing to Parkinson's disease (PD) pathology. A known ROS …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic
threat with more than 11.8 million confirmed cases and more than 0.5 million deaths as of 3 …

肥胖是一种全球性流行病, 与II 型糖尿病, 癌症和心血管疾病密切相关, 对人类健康构成了严重的
威胁. 近些年, 多种食源活性物质及其他生物活性因子已被证明可以通过诱导米色脂肪生成促进 …

摘要目的: 从干预组蛋白去乙酰化酶(Sirtuin1, SIRT1) 表达探究急性应激影响糖尿病小鼠葡萄糖
代谢和脂肪代谢的机制. 方法: 以30 只C57BL/6 小鼠为研究对象, 通过高脂饮食和链脲佐菌素 …

Expression of synphilin-1 in neurons induces hyperphagia and obesity in a Drosophila
model. However, the molecular pathways underlying synphilin-1-linked obesity remain …