The role of m6A RNA methylation in human cancer
XY Chen, J Zhang, JS Zhu - Molecular cancer, 2019 - Springer
Abstract N 6-methyladenosine (m 6 A) is identified as the most common, abundant and
conserved internal transcriptional modification, especially within eukaryotic messenger …
conserved internal transcriptional modification, especially within eukaryotic messenger …
Role of m6A RNA methylation in cardiovascular disease
Y Qin, L Li, E Luo, J Hou, G Yan… - International …, 2020 - spandidos-publications.com
Abstract N6‑methyladenosine (m6A) is the most prevalent and abundant type of internal post‑
transcriptional RNA modification in eukaryotic cells. Multiple types of RNA, including …
transcriptional RNA modification in eukaryotic cells. Multiple types of RNA, including …
m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome
Functional studies of the RNA N 6-methyladenosine (m6A) modification have been limited
by an inability to map individual m6A-modified sites in whole transcriptomes. To enable such …
by an inability to map individual m6A-modified sites in whole transcriptomes. To enable such …
YTHDF2 inhibition potentiates radiotherapy antitumor efficacy
Summary RNA N 6-methyladenosine (m 6 A) modification is implicated in cancer
progression. However, the impact of m 6 A on the antitumor effects of radiotherapy and the …
progression. However, the impact of m 6 A on the antitumor effects of radiotherapy and the …
The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells
Glioblastoma is a universally lethal cancer driven by glioblastoma stem cells (GSC). Here,
we interrogated N 6-methyladenosine (m6A) mRNA modifications in GSCs by methyl RNA …
we interrogated N 6-methyladenosine (m6A) mRNA modifications in GSCs by methyl RNA …
Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis
Abstract N 6-methyladenosine (m 6 A) is the most common internal modification in
eukaryotic mRNA. It is dynamically installed and removed, and acts as a new layer of mRNA …
eukaryotic mRNA. It is dynamically installed and removed, and acts as a new layer of mRNA …
METTL3 and ALKBH5 oppositely regulate m6A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes
H Song, X Feng, H Zhang, Y Luo, J Huang, M Lin… - Autophagy, 2019 - Taylor & Francis
ABSTRACT N6-methyladenosine (m6A) mRNA modifications play critical roles in various
biological processes. However, no study addresses the role of m6A in macroautophagy …
biological processes. However, no study addresses the role of m6A in macroautophagy …
MODOMICS: a database of RNA modification pathways. 2021 update
P Boccaletto, F Stefaniak, A Ray… - Nucleic acids …, 2022 - academic.oup.com
The MODOMICS database has been, since 2006, a manually curated and centralized
resource, storing and distributing comprehensive information about modified …
resource, storing and distributing comprehensive information about modified …
The RNA modification landscape in human disease
RNA modifications have been historically considered as fine-tuning chemo-structural
features of infrastructural RNAs, such as rRNAs, tRNAs, and snoRNAs. This view has …
features of infrastructural RNAs, such as rRNAs, tRNAs, and snoRNAs. This view has …
N6-methyladenosine modulates messenger RNA translation efficiency
Summary N 6-methyladenosine (m 6 A) is the most abundant internal modification in
mammalian mRNA. This modification is reversible and non-stoichiometric and adds another …
mammalian mRNA. This modification is reversible and non-stoichiometric and adds another …