Biodiversity of insects is threatened worldwide. Here, we present a comprehensive review of
73 historical reports of insect declines from across the globe, and systematically assess the …

Managed populations of the European honey bee (Apis mellifera) support the production of
a global food supply. This important role in modern agriculture has rendered honey bees …

Anthropogenic climate change and increasing antimicrobial resistance (AMR) together
threaten the last 50 years of public health gains. Honey bees are a model One Health …

Social bee gut microbiotas play key roles in host health and performance. Worryingly, a
growing body of literature shows that pesticide exposure can disturb these microbiotas. Most …

Neonicotinoids are among the most widely used insecticides in the world and are
recognized as a potential cause of pollinator decline. Previous studies have demonstrated …

Nicotinic acetylcholine receptors (nAChRs) are the main target of neonicotinoid insecticides,
which are widely used in crop protection against insect pests. Electrophysiological and …

Declines in native insect pollinator populations and substantial losses in managed honey
bees have been reported on a global scale and become a widespread concern because of …

Many insect species, including social insects, are currently declining in abundance and
diversity. Pollutants such as pesticides, heavy metals, or airborne fine particulate matter from …

Stressful conditions during development can have sub-lethal consequences on organisms
aside from mortality. Using previously reported in-hive residues from commercial colonies …

Acetylcholine (ACh) is the major excitatory neurotransmitter in the insect central nervous
system (CNS). However, besides the neuronal expression of ACh receptors (AChR), the …