Neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies
G Costa, MA De Luca, G Piras, J Marongiu… - Neural regeneration …, 2020 - journals.lww.com
Preclinical and clinical studies indicate that synthetic psychoactive substances, in addition to
having abuse potential, may elicit toxic effects of varying severity at the peripheral and …
having abuse potential, may elicit toxic effects of varying severity at the peripheral and …
Therapeutic effects of high-intensity interval training exercise alone and its combination with ecdysterone against amyloid beta-induced rat model of Alzheimer's …
Hippocampal oxidative stress has a vital role in the pathophysiology of Alzheimer's disease
(AD)-associated behavioral deficits. Ecdysterone (Ecdy), a natural product and primary …
(AD)-associated behavioral deficits. Ecdysterone (Ecdy), a natural product and primary …
Melatonin-pretreated adipose-derived mesenchymal stem cells efficeintly improved learning, memory, and cognition in an animal model of Alzheimer's disease
Currently, mesenchymal stem cells (MSCs) based therapy has extensive attraction for
Alzheimer's disease (AD). However, low survival rate of MSCs after transplantation is a huge …
Alzheimer's disease (AD). However, low survival rate of MSCs after transplantation is a huge …
The effect of NAD-299 and TCB-2 on learning and memory, hippocampal BDNF levels and amyloid plaques in Streptozotocin-induced memory deficits in male rats
Rationale Alzheimer's disease (AD) is the most common form of dementia characterized by
a progressive decline in cognitive function. The serotonergic system via the 5-HT1A receptor …
a progressive decline in cognitive function. The serotonergic system via the 5-HT1A receptor …
Minocycline effects on memory and learning impairment in the beta-amyloid-induced Alzheimer's disease model in male rats using behavioral, biochemical, and …
Abstract Alzheimer's disease (AD), as an advanced neurodegenerative disease, is
characterized by the everlasting impairment of memory, which is determined by …
characterized by the everlasting impairment of memory, which is determined by …
Similar tests of anxiety-like behavior yield different results: comparison of the open field and free exploratory rodent procedures
CN Snyder, AR Brown, D Buffalari - Physiology & behavior, 2021 - Elsevier
Pharmacological agents that treat anxiety disorders are often validated in animal models
prior to clinical trials. Yet results suggest little consistency in rodent anxiety-like behavior …
prior to clinical trials. Yet results suggest little consistency in rodent anxiety-like behavior …
Methamphetamine and REM sleep deprivation interact to affect behavioral performance in adult and adolescent rats
A Brimvandi, SE Nedaei, A Pourmotaabed, K Sahveisi… - Brain Research, 2024 - Elsevier
Drug addiction may result in sleep problems. Importantly, sleep deprivation (SD) is known as
an important risk factor for relapse to drug abuse as SD mimics the effects of …
an important risk factor for relapse to drug abuse as SD mimics the effects of …
Effectiveness of coenzyme Q10 on learning and memory and synaptic plasticity impairment in an aged Aβ-induced rat model of Alzheimer's disease: a behavioral …
Rationale Aging is the major risk factor for Alzheimer's disease (AD), and cognitive and
memory impairments are common among the elderly. Interestingly, coenzyme Q10 (Q10) …
memory impairments are common among the elderly. Interestingly, coenzyme Q10 (Q10) …
The effects of cinnamaldehyde on acute or chronic stress-induced anxiety-related behavior and locomotion in male mice
Anxiety and stress are considered as universal psychiatric exhibitions of the present
societies and lifestyles. Several experiments have been conducted to examine natural …
societies and lifestyles. Several experiments have been conducted to examine natural …
Protective effects of alpha-lipoic acid on anxiety-like behavior, memory and prevention of hippocampal oxidative stress in methamphetamine-treated rats
HMP Kargar, H Noshiri - Psychopharmacology, 2024 - Springer
Rationale Alpha-lipoic acid is an essential cofactor for aerobic metabolism and acts as a
potent antioxidant in the body. It has been shown that acute exposure to methamphetamine …
potent antioxidant in the body. It has been shown that acute exposure to methamphetamine …