State of the evidence 2017: an update on the connection between breast cancer and the environment

JM Gray, S Rasanayagam, C Engel, J Rizzo - Environmental Health, 2017 - Springer
Background In this review, we examine the continually expanding and increasingly
compelling data linking radiation and various chemicals in our environment to the current …

Progesterone and breast cancer

B Trabert, ME Sherman, N Kannan… - Endocrine …, 2020 - academic.oup.com
Synthetic progestogens (progestins) have been linked to increased breast cancer risk;
however, the role of endogenous progesterone in breast physiology and carcinogenesis is …

Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide

DR Cochrane, S Bernales, BM Jacobsen… - Breast Cancer …, 2014 - Springer
Introduction The androgen receptor (AR) is widely expressed in breast cancers and has
been proposed as a therapeutic target in estrogen receptor alpha (ER) negative breast …

Androgen receptor function and targeted therapeutics across breast cancer subtypes

EA Kolyvas, C Caldas, K Kelly, SS Ahmad - Breast Cancer Research, 2022 - Springer
Despite significant progress in breast cancer (BC) therapy, it is globally the most commonly
diagnosed cancer and leads to the death of over 650,000 women annually. Androgen …

Breast cancer development in transsexual subjects receiving cross-sex hormone treatment

LJ Gooren, MAA Van Trotsenburg… - The Journal of …, 2013 - academic.oup.com
Introduction Transsexual people receive cross-sex hormones as part of their treatment,
potentially inducing hormone-sensitive malignancies. Aim To examine the occurrence of …

Minireview: the androgen receptor in breast tissues: growth inhibitor, tumor suppressor, oncogene?

TE Hickey, JLL Robinson, JS Carroll… - Molecular …, 2012 - academic.oup.com
Androgen receptor (AR) signaling exerts an antiestrogenic, growth-inhibitory influence in
normal breast tissue, and this role may be sustained in estrogen receptor α (ERα)-positive …

Lavender products associated with premature thelarche and prepubertal gynecomastia: case reports and endocrine-disrupting chemical activities

JT Ramsey, Y Li, Y Arao, A Naidu… - The Journal of …, 2019 - academic.oup.com
Context Previous case reports associated prepubertal gynecomastia with lavender-
containing fragrances, but there appear to be no reports of premature thelarche. Objective …

Postmenopausal plasma sex hormone levels and breast cancer risk over 20 years of follow-up

X Zhang, SS Tworoger, AH Eliassen… - Breast cancer research …, 2013 - Springer
Plasma estrogen and androgen levels are positively associated with postmenopausal breast
cancer risk, but how long a single blood measurement can predict risk and whether the …

The expression and clinical significance of the androgen receptor and E-cadherin in triple-negative breast cancer

D Tang, S Xu, Q Zhang, W Zhao - Medical oncology, 2012 - Springer
Triple-negative breast cancer (TNBC) has a poor prognosis and lacks prognostic indicators.
The androgen receptor (AR) and E-cadherin are involved in the pathogenesis of breast …

Driving forces of technological change in medicine: Radical innovations induced by side effects and their impact on society and healthcare

M Coccia - Technology in Society, 2012 - Elsevier
Technological change in medicine has complex interactions driven by demand-and supply
side determinants. The epistemological position of this paper is that scientific research …