Vitamin D as a Modulator of Neuroinflammation: Implications for Brain Health

SG Menéndez, W Manucha - Current Pharmaceutical Design, 2024 - ingentaconnect.com
Neuroinflammation represents a critical immune response within the brain, playing a pivotal
role in defense against injury and infection. However, when this response becomes chronic …

Glial cells are affected more than interneurons by the loss of Engrailed 2 gene in the mouse cerebellum

G Lazzarini, A Gatta, V Miragliotta, F Vaglini… - Journal of …, 2024 - Wiley Online Library
Glial cells play a pivotal role in the inflammatory processes, which are common features of
several neurodevelopmental and neurodegenerative disorders. Their major role in …

[HTML][HTML] Neuroinflammation increases oxygen extraction in a mouse model of Alzheimer's disease

C Liu, A Cárdenas-Rivera, S Teitelbaum… - Alzheimer's Research & …, 2024 - Springer
Background Neuroinflammation, impaired metabolism, and hypoperfusion are fundamental
pathological hallmarks of early Alzheimer's disease (AD). Numerous studies have asserted …

β2-Adrenoceptor agonist formoterol attenuates NLRP3 inflammasome activation and GSDMD-mediated pyroptosis in microglia through enhancing IκBα/NF-κB …

M Erdem, Ş Erdem, A Alver, TR Kıran… - Molecular and Cellular …, 2024 - Elsevier
Microglia are immune cells that play important roles in the formation of the innate immune
response within the central nervous system (CNS). The NOD-like receptor family pyrin …