Cobalt metabolism and toxicology—a brief update

LO Simonsen, H Harbak, P Bennekou - Science of the Total Environment, 2012 - Elsevier
Cobalt metabolism and toxicology are summarized. The biological functions of cobalt are
updated in the light of recent understanding of cobalt interference with the sensing in almost …

Metal-on-metal bearings: the evidence so far

FS Haddad, RR Thakrar, AJ Hart… - The Journal of Bone …, 2011 - boneandjoint.org.uk
Lately, concerns have arisen following the use of large metal-on-metal bearings in hip
replacements owing to reports of catastrophic soft-tissue reactions resulting in implant failure …

Accelerating failure rate of the ASR total hip replacement

DJ Langton, SS Jameson, TJ Joyce… - The Journal of Bone …, 2011 - boneandjoint.org.uk
There is widespread concern regarding the incidence of adverse soft-tissue reactions after
metal-on-metal (MoM) hip replacement. Recent National Joint Registry data have shown …

Metal-on-metal hip arthroplasty: a review of adverse reactions and patient management

J Drummond, P Tran, C Fary - Journal of functional biomaterials, 2015 - mdpi.com
Recent alarming joint registry data highlighting increased revision rates has prompted
further research into the area of metal-on-metal hip replacements and resurfacings. This …

Biocompatibility considerations in the design of graphene biomedical materials

CJ Bullock, C Bussy - Advanced Materials Interfaces, 2019 - Wiley Online Library
Graphene‐based materials (GBM) have outstanding properties that have proven highly
beneficial in several proof‐of‐concept investigations on their biomedical potential. They can …

Graphitic tribological layers in metal-on-metal hip replacements

Y Liao, R Pourzal, MA Wimmer, JJ Jacobs, A Fischer… - Science, 2011 - science.org
Arthritis is a leading cause of disability, and when nonoperative methods have failed, a
prosthetic implant is a cost-effective and clinically successful treatment. Metal-on-metal …

High incidence of pseudotumour formation after large-diameter metal-on-metal total hip replacement: a prospective cohort study

BH Bosker, HB Ettema, MF Boomsma… - The Journal of Bone …, 2012 - boneandjoint.org.uk
Peri-articular soft-tissue masses or 'pseudotumours' can occur after large-diameter metal-on-
metal (MoM) resurfacing of the hip and conventional total hip replacement (THR). Our aim …

CoCrMo metal-on-metal hip replacements

Y Liao, E Hoffman, M Wimmer, A Fischer… - Physical Chemistry …, 2013 - pubs.rsc.org
After the rapid growth in the use of CoCrMo metal-on-metal hip replacements since the
second generation was introduced circa 1990, metal-on-metal hip replacements have …

Hyaluronic acid–British anti-Lewisite as a safer chelation therapy for the treatment of arthroplasty-related metallosis

CC Ude, SJ Schmidt, S Laurencin… - Proceedings of the …, 2023 - National Acad Sciences
Cobalt-containing alloys are useful for orthopedic applications due to their low volumetric
wear rates, corrosion resistance, high mechanical strength, hardness, and fatigue …

Direct in vivo inflammatory cell‐induced corrosion of CoCrMo alloy orthopedic implant surfaces

JL Gilbert, S Sivan, Y Liu, SB Kocagöz… - … Research Part A, 2015 - Wiley Online Library
Abstract Cobalt–chromium–molybdenum (CoCrMo) alloy, used for over five decades in
orthopedic implants, may corrode and release wear debris into the body during use. These …