Multifunctional roles and pharmacological potential of β-sitosterol: Emerging evidence toward clinical applications

Z Khan, N Nath, A Rauf, TB Emran, S Mitra… - Chemico-Biological …, 2022 - Elsevier
Currently, available therapeutic medications are both costly as well as not entirely promising
in terms of potency. So, new candidates from natural resources are of research interest to …

Sesame Seeds: A Nutrient-Rich Superfood

P Mostashari, A Mousavi Khaneghah - Foods, 2024 - mdpi.com
Sesame seeds (Sesamum indicum L.) have been cultivated for thousands of years and have
long been celebrated for their culinary versatility. Beyond their delightful nutty flavor and …

[HTML][HTML] Interplay between NADH oxidation by complex I, glutathione redox state and sirtuin-3, and its role in the development of insulin resistance

C Cortés-Rojo, MA Vargas-Vargas… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Metabolic diseases are characterized by high NADH/NAD+ ratios due to excessive electron
supply, causing defective mitochondrial function and impaired sirtuin-3 (SIRT-3) activity, the …

Irbesartan attenuates gentamicin-induced nephrotoxicity in rats through modulation of oxidative stress and endogenous antioxidant capacity

HM Al-Kuraishy, AI Al-Gareeb… - International journal of …, 2020 - journals.lww.com
Background: Overproduction of reactive oxygen species and free radicals is the main
mechanism beyond gentamicin-induced nephrotoxicity. Irbesartan and other angiotensin II …

Linking phytosterols and oxyphytosterols from food to brain health: origins, effects, and underlying mechanisms

F Jie, X Yang, L Wu, M Wang, B Lu - Critical reviews in food …, 2022 - Taylor & Francis
Phytosterols and their oxidation products, namely oxyphytosterols, are natural compounds
present in plant foods. With increased intake of phytosterol-enriched functional food …

β‐Sitosterol Alters the Inflammatory Response in CLP Rat Model of Sepsis by Modulation of NFκB Signaling

S Kasirzadeh, MH Ghahremani… - BioMed research …, 2021 - Wiley Online Library
Purpose. Sepsis originates from the host inflammatory response, especially to bacterial
infections, and is considered one of the main causes of death in intensive care units. Various …

[HTML][HTML] Analysis of antioxidative and antiviral biomarkers β-amyrin, β-sitosterol, lupeol, ursolic acid in Guiera senegalensis leaves extract by validated HPTLC …

MK Parvez, P Alam, AH Arbab, MS Al-Dosari… - Saudi pharmaceutical …, 2018 - Elsevier
Guiera senegalensis JF Gmel is a broad-spectrum African folk-medicinal plant, having
activities against fowlpox and herpes viruses. Very recently, we have shown the anti …

Vinpocetine improves oxidative stress and pro-inflammatory mediators in acute kidney injury

HM Al-Kuraishy, AI Al-Gareeb… - International journal of …, 2019 - journals.lww.com
Background: Gentamicin-induced-acute kidney injury (AKI) is a multifaceted phenomenon
which previously linked to the oxidative stress only. Vinpocetine prevents reactive free …

β‐Sitosterol Protects against Myocardial Ischemia/Reperfusion Injury via Targeting PPARγ/NF‐κB Signalling

F Lin, L Xu, M Huang, B Deng, W Zhang… - Evidence‐Based …, 2020 - Wiley Online Library
Myocardial ischemia/reperfusion (I/R) injury is a clinically severe complication, which can
cause high rates of disability and mortality particularly in patients with myocardial infarction …

[HTML][HTML] Exploring the therapeutic potential of edible Pleurotus mushroom species for oxidative stress and diabetes management

KV Krishna, JM Murugan, H Khan, M Kumar… - Journal of King Saud …, 2023 - Elsevier
Objectives In this study, extracts from eight Pleurotus mushroom species were examined for
their antioxidant properties. Methods The pure cultures of eight Pleurotus were grown …