Metallothioneins (MTs) are ubiquitous metal-chelating proteins involved in cellular metal
homeostasis. MTs were found to be related with almost all the biological processes and their …

Multicellular organisms rely on cell–cell communication to exchange information necessary
for developmental processes and metabolic homeostasis. Cell–cell communication …

Ursolic acid (UA) is a bioactive molecule widely distributed in various fruits and vegetables,
which was reported to play a therapeutic role in ulcerative colitis (UC) induced by toxic …

Female reproduction comes at great expense to energy metabolism compensated by
extensive organ adaptations including intestinal size. Upon mating, endocrine signals …

Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool for studying
complex cellular composition and gene expression dynamics of biological systems. In this …

Insect midgut plays a central role in food digestion and nutrition absorption. Larval silkworm
midgut could be divided into 3 distinct regions based on their morphological colors …

The explosive growth of regulatory hypotheses from single-cell datasets demands accurate
prioritization of hypotheses for in vivo validation. However, current computational methods …

The mosquito midgut functions as a key interface between pathogen and vector. However,
studies of midgut physiology and associated virus infection dynamics are scarce, and in …

Age-related loss of intestinal barrier function has been documented across species, but the
causes remain unknown. The intestinal barrier is maintained by tight junctions (TJs) in …

The development of a multicellular organism is a highly intricate process tightly regulated by
numerous genes and pathways in both spatial and temporal manners. Here, we present …