Immune-checkpoint blockers (ICBs) have revolutionized oncology and firmly established the
subfield of immuno-oncology. Despite this renaissance, a subset of cancer patients remain …

The activation of nuclear factor-kappaB (NFΚB), a proinflammatory transcription factor, is a
commonly observed phenomenon in breast cancer. It facilitates the development of a …

Annexin A1 (ANXA1) is a phospholipid-linked protein involved in inflammation, immune
response, and mast cell reactivity. Recently, we reported that ANXA1 is associated with …

Background: Necroptosis, a cell death of caspase-independence, plays a pivotal role in
cancer biological regulation. Although necroptosis is closely associated with oncogenesis …

Receptor-interacting protein kinase 1 (RIPK1) represents an essential signaling node in cell
death and inflammation. Ablation of Ripk1 in liver parenchymal cells (LPC) did not cause a …

Annexin A1 (ANXA1) is a Ca2+-regulated phospholipid-binding protein involved in various
cell processes. ANXA1 was initially widely studied in inflammation resolution, but its …

The deregulation of Annexin A1 (ANXA1), a regulator of inflammation and immunity, leads to
cancer growth and metastasis. However, whether ANXA1 is involved in cancer …

Annexin-A1 (ANXA1), a potent endogenous immunomodulatory protein has been implicated
in multiple functions essential in cancer, including cell proliferation, apoptosis …

Macrophages are potent immune cells with well-established roles in the response to stress,
injury, infection and inflammation. The classically activated macrophages (M1) are induced …

Abstract Annexin A1 (ANXA1) is dysregulated in the various tumors. However, the role and
mechanism of ANXA1 in the cancers are poorly understood. In this study, we first showed a …