[HTML][HTML] Placental structure in gestational diabetes mellitus

I Carrasco-Wong, A Moller, FR Giachini… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The placenta is a transitory organ, located between the mother and the foetus, which
supports intrauterine life. This organ has nutritional, endocrine and immunologic functions to …

[HTML][HTML] Effects of maternal diabetes on trophoblast cells

MB Aires, ACV Dos Santos - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) is a health condition characterized by hyperglycemia over a
prolonged period. There are three main types of DM: DM type 1 (DM1), DM2 and gestational …

[HTML][HTML] Integrated transcriptome sequencing analysis reveals role of miR-138-5p/TBL1X in placenta from gestational diabetes mellitus

R Ding, F Guo, Y Zhang, XM Liu, YQ Xiang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: The placenta has been suggested to play a crucial role in the pathology
of gestational diabetes mellitus (GDM). Placenta-specific microRNAs (miRNAs) and the …

[HTML][HTML] Placental homing peptide-microRNA inhibitor conjugates for targeted enhancement of intrinsic placental growth signaling

F Beards, LE Jones, J Charnock, K Forbes… - Theranostics, 2017 - ncbi.nlm.nih.gov
Suboptimal placental growth and development are the underlying cause of many pregnancy
complications. No treatments are available, primarily due to the risk of causing fetal …

[HTML][HTML] Type 1 diabetes mellitus and the first trimester placenta: hyperglycemia-induced effects on trophoblast proliferation, cell cycle regulators, and invasion

A Majali-Martinez, U Weiss-Fuchs, H Miedl… - International Journal of …, 2021 - mdpi.com
Type 1 diabetes mellitus (T1DM) is associated with reduced fetal growth in early pregnancy,
but a contributing role of the placenta has remained elusive. Thus, we investigated whether …

Decreased placental apoptosis and autophagy in pregnancies complicated by gestational diabetes with large-for-gestational age fetuses

TH Hung, SY Huang, SF Chen, CP Wu - Placenta, 2020 - Elsevier
Introduction Dysregulation of placental apoptosis and autophagy are observed in pregnancy
complications including preeclampsia and fetal growth restriction. However, studies of their …

PFOS-induced placental cell growth inhibition is partially mediated by lncRNA H19 through interacting with miR-19a and miR-19b

J Li, X Quan, G Chen, J Hong, Q Wang, L Xu, B Wang… - Chemosphere, 2020 - Elsevier
Perfluorooctane sulfonic acid (PFOS), a persistent environmental pollutant, has been
associated with decreased birth weight. The dysregulation of long non-coding RNA …

Decreased expression and activation of Stat3 in severe preeclampsia

Z Zhang, X Yang, L Zhang, Z Duan, L Jia… - Journal of molecular …, 2015 - Springer
Severe preeclampsia (PE) is a major cause of maternal mortality and morbidity worldwide.
Signal transducer and activator of transcription 3 (Stat3) signal pathway can modulate …

[HTML][HTML] The role, mechanism and potentially novel biomarker of microRNA-17-92 cluster in macrosomia

J Li, L Chen, Q Tang, W Wu, H Gu, L Liu, J Wu… - Scientific Reports, 2015 - nature.com
Macrosomia is one of the most common perinatal complications of pregnancy and has life-
long health implications for the infant. microRNAs (miRNAs) have been identified to regulate …

Prenatal aripiprazole induces alterations of rat placenta: a histological, immunohistochemical and ultrastructural study

MA Othman, M Husni, WAN El-Din, AH Salem… - Journal of Molecular …, 2024 - Springer
Antipsychotic drugs (APDs) are used to treat many psychiatric illnesses as schizophrenia.
Typical antipsychotic drugs (TAPDs) are being used; however, they have many side effects …