Fragile X syndrome (FXS), the most common genetic form of intellectual disability in males,
is caused by silencing of the FMR1 gene associated with hypermethylation of the CGG …

The pathological alterations that manifest during the early embryonic development due to
inherited and acquired factors trigger various neurodevelopmental disorders (NDDs) …

Autism spectrum disorders are a group of pervasive neurodevelopmental conditions with
heterogeneous etiology, characterized by deficits in social cognition, communication, and …

Fragile X syndrome (FXS) is an X chromosome–linked disease leading to severe intellectual
disabilities. FXS is caused by inactivation of the fragile X mental retardation 1 (FMR1) gene …

Fragile X syndrome (FXS), the most prevalent heritable form of intellectual disability, is
caused by the transcriptional silencing of the FMR1 gene. While neuronal contribution to …

Although numerous protocols have been developed for differentiation of neurons from a
variety of pluripotent stem cells, most have concentrated on being able to specify effectively …

Autism spectrum disorder (ASD) represents a group of neurodevelopmental diseases
characterized by persistent deficits in social communication, interaction, and repetitive …

Human patient-derived induced pluripotent stem cells (hiPSCs) provide unique
opportunities for disease modeling and drug development. However, adapting hiPSCs or …

Autism spectrum disorders (ASDs) are characterized by core domains: persistent deficits in
social communication and interaction; restricted, repetitive patterns of behavior, interests, or …

Abstract Autism Spectrum Disorder (ASD) is caused by genetic, epigenetic, and
environmental factors. Mutations in the human FMR1 gene, encoding the Fragile X …