Natural products and their derivatives: Promising modulators of tumor immunotherapy
LJ Deng, M Qi, N Li, YH Lei, DM Zhang… - Journal of Leucocyte …, 2020 - academic.oup.com
A wealth of evidence supports the role of tumor immunotherapy as a vital therapeutic option
in cancer. In recent decades, accumulated studies have revealed the anticancer activities of …
in cancer. In recent decades, accumulated studies have revealed the anticancer activities of …
Consensus guidelines for the detection of immunogenic cell death
O Kepp, L Senovilla, I Vitale, E Vacchelli… - …, 2014 - Taylor & Francis
Apoptotic cells have long been considered as intrinsically tolerogenic or unable to elicit
immune responses specific for dead cell-associated antigens. However, multiple stimuli can …
immune responses specific for dead cell-associated antigens. However, multiple stimuli can …
[HTML][HTML] Cytokines in immunogenic cell death: applications for cancer immunotherapy
A Showalter, A Limaye, JL Oyer, R Igarashi… - Cytokine, 2017 - Elsevier
Despite advances in treatments like chemotherapy and radiotherapy, metastatic cancer
remains a leading cause of death for cancer patients. While many chemotherapeutic agents …
remains a leading cause of death for cancer patients. While many chemotherapeutic agents …
Molecular pathways: the immunogenic effects of platinum-based chemotherapeutics
SV Hato, A Khong, IJM de Vries, WJ Lesterhuis - Clinical Cancer Research, 2014 - AACR
The platinum-based drugs cisplatin, carboplatin, and oxaliplatin belong to the most widely
used chemotherapeutics in oncology, showing clinical efficacy against many solid tumors …
used chemotherapeutics in oncology, showing clinical efficacy against many solid tumors …
[HTML][HTML] Molecular mechanisms of ATP secretion during immunogenic cell death
I Martins, Y Wang, M Michaud, Y Ma… - Cell Death & …, 2014 - nature.com
The immunogenic demise of cancer cells can be induced by various chemotherapeutics,
such as anthracyclines and oxaliplatin, and provokes an immune response against tumor …
such as anthracyclines and oxaliplatin, and provokes an immune response against tumor …
Dendritic cells as gatekeepers of tolerance
A Waisman, D Lukas, BE Clausen, N Yogev - Seminars in …, 2017 - Springer
Dendritic cells (DC) are unique hematopoietic cells, linking innate and adaptive immune
responses. In particular, they are considered as the most potent antigen presenting cells …
responses. In particular, they are considered as the most potent antigen presenting cells …
Trial Watch: Immunogenic cell death inducers for anticancer chemotherapy
The term “immunogenic cell death”(ICD) is now employed to indicate a functionally peculiar
form of apoptosis that is sufficient for immunocompetent hosts to mount an adaptive immune …
form of apoptosis that is sufficient for immunocompetent hosts to mount an adaptive immune …
[HTML][HTML] Realizing the clinical potential of immunogenic cell death in cancer chemotherapy and radiotherapy
BL Rapoport, R Anderson - International journal of molecular sciences, 2019 - mdpi.com
Immunogenic cell death (ICD), which is triggered by exposure of tumor cells to a limited
range of anticancer drugs, radiotherapy, and photodynamic therapy, represents a recent …
range of anticancer drugs, radiotherapy, and photodynamic therapy, represents a recent …
[HTML][HTML] Plant glycosides and glycosidases: a treasure-trove for therapeutics
K Kytidou, M Artola, HS Overkleeft… - Frontiers in plant …, 2020 - frontiersin.org
Plants contain numerous glycoconjugates that are metabolized by specific
glucosyltransferases and hydrolyzed by specific glycosidases, some also catalyzing …
glucosyltransferases and hydrolyzed by specific glycosidases, some also catalyzing …
Sodium homeostasis in the tumour microenvironment
The concentration of sodium ions (Na+) is raised in solid tumours and can be measured at
the cellular, tissue and patient levels. At the cellular level, the Na+ gradient across the …
the cellular, tissue and patient levels. At the cellular level, the Na+ gradient across the …