Plant natural products are of great value for agriculture, medicine and a wide range of other
industrial applications. The discovery of new plant natural product pathways is currently …

Benzylisoquinoline alkaloids (BIAs) are a structurally diverse group of plant specialized
metabolites with a long history of investigation. Although the ecophysiological functions of …

Alkaloids represent a highly diverse group of compounds that are related only by the
occurrence of a nitrogen atom in a heterocyclic ring. Plants are estimated to produce …

Noscapine is an antitumor alkaloid from opium poppy that binds tubulin, arrests metaphase,
and induces apoptosis in dividing human cells. Elucidation of the biosynthetic pathway will …

Opium poppy (Papaver somniferum) is one of the world's oldest medicinal plants and
remains the only commercial source for the narcotic analgesics morphine, codeine and semi …

Covering: up to January 2012 The addition of a methyl moiety to a small chemical is a
common transformation in the biosynthesis of natural products across all three domains of …

Benzylisoquinoline alkaloids (BIAs) represent a large class of plant secondary metabolites,
including pharmaceuticals such as morphine, codeine and their derivatives. Large-scale …

Noscapine is a potential anticancer drug isolated from the opium poppy Papaver
somniferum, and genes encoding enzymes responsible for the synthesis of noscapine have …

Alkaloids represent a large and diverse group of compounds that are related by the
occurrence of a nitrogen atom within a heterocyclic backbone. Unlike other types of …

For nearly eight millennia, opium poppy (Papaver somniferum) has been bred and cultivated
for therapeutic purposes. The medicinal properties of the plant are conferred by specialized …