An In Silico Bioremediation Study to Identify Essential Residues of Metallothionein Enhancing the Bioaccumulation of Heavy Metals in Pseudomonas aeruginosa

M Tasleem, WM Hussein, AAAA El-Sayed, A Alrehaily - Microorganisms, 2023 - mdpi.com
Microorganisms are ubiquitously present in the environment and exert significant influence
on numerous natural phenomena. The soil and groundwater systems, precipitation, and …

Exploring Major Flavonoid Phytochemicals from Nelumbo nucifera Gaertn. as Potential Skin Anti-Aging Agents: In Silico and In Vitro Evaluations

B Nutho, D Tungmunnithum - International Journal of Molecular Sciences, 2023 - mdpi.com
Nelumbo nucifera Gaertn., an aquatic medicinal plant (Nelumbonaceae family), has a
history of use in traditional medicine across various regions. Our previous study …

Identification of Fungicide Combinations Targeting Plasmopara viticola and Botrytis cinerea Fungicide Resistance Using Machine Learning

J Zhang, SD Fernando - Microorganisms, 2023 - mdpi.com
Downy mildew (caused by Plasmopara viticola) and gray mold (caused by Botrytis cinerea)
are fungal diseases that significantly impact grape production globally. Cytochrome b plays …

Effect of lactobacteria on bioactive peptides and their sequence identification in mature cheese

M Kurbanova, R Voroshilin, O Kozlova, V Atuchin - Microorganisms, 2022 - mdpi.com
An in silico study that featured the effect of starter cultures on the bioactivity and other health
benefits of peptides in semi-hard cheese is presented in this contribution. Model Caciotta …

Integration of Phosphoproteomics and Transcriptome Studies Reveals ABA Signaling Pathways Regulate UV-B Tolerance in Rhododendron chrysanthum Leaves

Q Sun, X Zhou, L Yang, H Xu, X Zhou - Genes, 2023 - mdpi.com
The influence of UV-B stress on the growth, development, and metabolism of alpine plants,
such as the damage to DNA macromolecules, the decline in photosynthetic rate, and …

SARS-CoV-2 Papain-like Protease Responsive ZnO/Daclatasvir-Loaded Chitosan/Gelatin Nanofibers as Smart Antimicrobial Medical Textiles: In Silico, In Vitro and …

M Hamdi, AM Elkashlan, MA Hammad, IH Ali - Pharmaceutics, 2023 - mdpi.com
A significant number of deaths are reported annually worldwide due to microbial and viral
infections. The development of protective medical textiles for patients and healthcare …

Unveiling the role of sorghum RPAP3 in the function of R2TP complex: insights into protein assembly in plants

LM Antonio, GH Martins, AZB Aragão, NG Quel… - Plants, 2023 - mdpi.com
The chaperone R2TP has multiple subunits that assist in the proper folding, assembly, and
stabilization of various protein complexes in cells and its study can offer valuable insights …

Exploring the Deoxy-D-xylulose-5-phosphate Synthase Gene Family in Tomato (Solanum lycopersicum)

X Di, M Rodriguez-Concepcion - Plants, 2023 - mdpi.com
Isoprenoids are a wide family of metabolites including high-value chemicals, flavors,
pigments, and drugs. Isoprenoids are particularly abundant and diverse in plants. The …

Synthesis of Pyrrolo[3,4-b]pyridin-5-ones via Ugi–Zhu Reaction and In Vitro–In Silico Studies against Breast Carcinoma

I Morales-Salazar, CE Garduño-Albino… - Pharmaceuticals, 2023 - mdpi.com
An Ugi–Zhu three-component reaction (UZ-3CR) coupled in a one-pot manner to a cascade
process (N-acylation/aza Diels–Alder cycloaddition/decarboxylation/dehydration) was …

Structural similarities and overlapping activities among Dihydroflavonol 4-Reductase, Flavanone 4-Reductase, and anthocyanidin reductase offer metabolic flexibility …

JA Lewis, B Zhang, R Harza, N Palmer… - International Journal of …, 2023 - mdpi.com
Flavonoids are potent antioxidants that play a role in defense against pathogens, UV-
radiation, and the detoxification of reactive oxygen species. Dihydroflavonol 4-reductase …