Current trends in computer aided drug design and a highlight of drugs discovered via computational techniques: A review

VT Sabe, T Ntombela, LA Jhamba… - European Journal of …, 2021 - Elsevier
Computer-aided drug design (CADD) is one of the pivotal approaches to contemporary pre-
clinical drug discovery, and various computational techniques and software programs are …

Fungal mushrooms: a natural compound with therapeutic applications

RM Chugh, P Mittal, N Mp, T Arora… - Frontiers in …, 2022 - frontiersin.org
Fungi are extremely diverse in terms of morphology, ecology, metabolism, and phylogeny.
Approximately, 130 medicinal activities like antitumor, immunomodulation, antioxidant …

Advanced methods for natural products discovery: bioactivity screening, dereplication, metabolomics profiling, genomic sequencing, databases and informatic tools …

SP Gaudêncio, E Bayram, L Lukić Bilela, M Cueto… - Marine drugs, 2023 - mdpi.com
Natural Products (NP) are essential for the discovery of novel drugs and products for
numerous biotechnological applications. The NP discovery process is expensive and time …

From traditional ethnopharmacology to modern natural drug discovery: A methodology discussion and specific examples

S Pirintsos, A Panagiotopoulos, M Bariotakis… - Molecules, 2022 - mdpi.com
Ethnopharmacology, through the description of the beneficial effects of plants, has provided
an early framework for the therapeutic use of natural compounds. Natural products, either in …

[HTML][HTML] A systematic review of computational approaches to understand cancer biology for informed drug repurposing

F Ahmed, A Samantasinghar, AM Soomro, S Kim… - Journal of Biomedical …, 2023 - Elsevier
Cancer is the second leading cause of death globally, trailing only heart disease. In the
United States alone, 1.9 million new cancer cases and 609,360 deaths were recorded for …

Intermolecular interactions between nitrosourea and polyoxometalate compounds

MD Mohammadi, F Abbas, H Louis… - …, 2022 - Wiley Online Library
Herein, the aim of this work was to investigate the intermolecular interactions between
polyoxometalate (POMs) as a drug‐delivery system with nitrosourea at different sites: CH3 …

From lock-in to transformation: A path-centric theory of emerging technology and organizing

BT Pentland, Y Yoo, J Recker, I Kim - Organization Science, 2022 - pubsonline.informs.org
We offer a path-centric theory of emerging technology and organizing that addresses a basic
question. When does emerging technology lead to transformative change? A path-centric …

[HTML][HTML] Computer-aided drug design in anti-cancer drug discovery: What have we learnt and what is the way forward?

O Iwaloye, PO Ottu, F Olawale, OO Babalola… - Informatics in Medicine …, 2023 - Elsevier
The escalating prevalence of cancer on a global scale, coupled with the inadequacies of
present-day therapies and the emergence of drug-resistant cancer strains, has necessitated …

How far have we explored fungi to fight cancer?

CW How, YS Ong, SS Low, A Pandey, PL Show… - Seminars in cancer …, 2022 - Elsevier
The use of fungal cultures have been well documented in human history. Although its used
in healthcare, like penicillin and statins, have saved countless of lives, but there is still no …

The new era of drug discovery: The power of computer-aided drug design (CADD)

IJS Nascimento, TM de Aquino… - Letters in Drug …, 2022 - ingentaconnect.com
Drug design and discovery is a process that requires high financial costs and is
timeconsuming. For many years, this process focused on empirical pharmacology. However …