Although use of the term “theranostic” is relatively recent, the concept goes back to the
earliest days of nuclear medicine, with the use of radioiodine for diagnosis and therapy of …

In this review, we examine the chelating ligand design and coordination complexes of
radioactive lanthanide isotopes. Where appropriate, discussion is placed in the context of …

Anti-CD20 radioimmunotherapy is an effective approach for therapy of relapsed or refractory
CD20pos lymphomas, but faces limitations due to poor tumor penetration and undesirable …

Lymphoma is a heterogeneous disease with varying clinical manifestations and outcomes.
Many subtypes of lymphoma, such as Burkitt′ s lymphoma and diffuse large B cell …

Prostate specific membrane antigen (PSMA) is an excellent target for imaging and treatment
of prostate carcinoma (PCa). Unfortunately, not all PCa cells express PSMA. Therefore …

Introduction: Radioimmunoconjugates have been used for 30 years to diagnose and treat
cancer. For many years, the use of these therapeutic tools has been limited to …

There are few effective therapies for small cell lung cancer (SCLC), a highly aggressive
disease representing 15% of total lung cancers. With median survival< 2 years, SCLC is one …

Melanoma is a cancer with increasing incidence and there is a need for alternatives to
immunotherapy within effective approaches to treatment of metastatic melanoma. We …

There has been considerable interest in developing a monoclonal antibody (mAb) against-
CD-20 (for example, Rituximab) modified by bifunctional chelating agents (BCA) for non …

In the last two decades, science has largely evolved in methodologies for cancer treatment,
yet, the basic backbone of cancer treatment includes surgery, chemotherapy and radiation …