Epicardial adipose tissue in contemporary cardiology
G Iacobellis - Nature reviews cardiology, 2022 - nature.com
Interest in epicardial adipose tissue (EAT) is growing rapidly, and research in this area
appeals to a broad, multidisciplinary audience. EAT is unique in its anatomy and …
appeals to a broad, multidisciplinary audience. EAT is unique in its anatomy and …
Obesity and cardiovascular disease: a scientific statement from the American Heart Association
TM Powell-Wiley, P Poirier, LE Burke, JP Després… - Circulation, 2021 - Am Heart Assoc
The global obesity epidemic is well established, with increases in obesity prevalence for
most countries since the 1980s. Obesity contributes directly to incident cardiovascular risk …
most countries since the 1980s. Obesity contributes directly to incident cardiovascular risk …
Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications
The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …
to the rapidly increased prevalence of overweight and obesity. To this point …
COVID-19 and diabetes: Can DPP4 inhibition play a role?
G Iacobellis - Diabetes research and clinical …, 2020 - diabetesresearchclinicalpractice …
In general, people with diabetes are at higher risk to develop complications when they are
infected with a virus. Type 2 diabetes, the most common type of diabetes, is associated with …
infected with a virus. Type 2 diabetes, the most common type of diabetes, is associated with …
Overview of epidemiology and contribution of obesity and body fat distribution to cardiovascular disease: an update
Obesity is recognized as a heterogeneous condition in which individuals with similar body
mass index may have distinct metabolic and cardiovascular risk profiles. Susceptibility to …
mass index may have distinct metabolic and cardiovascular risk profiles. Susceptibility to …
Non-canonical WNT signalling in cardiovascular disease: mechanisms and therapeutic implications
I Akoumianakis, M Polkinghorne… - Nature Reviews …, 2022 - nature.com
WNT signalling comprises a diverse spectrum of receptor-mediated pathways activated by a
large family of WNT ligands and influencing fundamental biological processes. WNT …
large family of WNT ligands and influencing fundamental biological processes. WNT …
Epicardial adipose tissue may mediate deleterious effects of obesity and inflammation on the myocardium
M Packer - Journal of the American College of Cardiology, 2018 - jacc.org
Epicardial adipose tissue has unique properties that distinguish it from other depots of
visceral fat. Rather than having distinct boundaries, the epicardium shares an unobstructed …
visceral fat. Rather than having distinct boundaries, the epicardium shares an unobstructed …
Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus: cardiovascular and kidney effects, potential mechanisms, and clinical applications
Sodium-glucose cotransporter-2 (SGLT2) inhibitors, including empagliflozin, dapagliflozin,
and canagliflozin, are now widely approved antihyperglycemic therapies. Because of their …
and canagliflozin, are now widely approved antihyperglycemic therapies. Because of their …
The role of adipose tissue in cardiovascular health and disease
EK Oikonomou, C Antoniades - Nature Reviews Cardiology, 2019 - nature.com
Accumulating knowledge on the biology and function of the adipose tissue has led to a
major shift in our understanding of its role in health and disease. The adipose tissue is now …
major shift in our understanding of its role in health and disease. The adipose tissue is now …
Hypertension, diabetes, atherosclerosis and NASH: cause or consequence?
Non-alcoholic fatty liver disease (NAFLD) has become one of the most common forms of
chronic liver disease worldwide and its prevalence is expected to continue rising. NAFLD …
chronic liver disease worldwide and its prevalence is expected to continue rising. NAFLD …