Global impacts of western diet and its effects on metabolism and health: A narrative review

VJ Clemente-Suárez, AI Beltrán-Velasco… - Nutrients, 2023 - mdpi.com
The Western diet is a modern dietary pattern characterized by high intakes of pre-packaged
foods, refined grains, red meat, processed meat, high-sugar drinks, candy, sweets, fried …

Impact of obesity on influenza A virus pathogenesis, immune response, and evolution

R Honce, S Schultz-Cherry - Frontiers in immunology, 2019 - frontiersin.org
With the rising prevalence of obesity has come an increasing awareness of its impact on
communicable disease. As a consequence of the 2009 H1N1 influenza A virus pandemic …

Dietary fructose improves intestinal cell survival and nutrient absorption

SR Taylor, S Ramsamooj, RJ Liang, A Katti… - Nature, 2021 - nature.com
Fructose consumption is linked to the rising incidence of obesity and cancer, which are two
of the leading causes of morbidity and mortality globally,. Dietary fructose metabolism …

Hyperinsulinaemia in cancer

EJ Gallagher, D LeRoith - Nature Reviews Cancer, 2020 - nature.com
Elevated circulating insulin levels are frequently observed in the setting of obesity and early
type 2 diabetes, as a result of insensitivity of metabolic tissues to the effects of insulin. Higher …

Small animal models of heart failure

C Riehle, J Bauersachs - Cardiovascular research, 2019 - academic.oup.com
Heart disease is a major cause of death worldwide with increasing prevalence, which urges
the development of new therapeutic strategies. Over the last few decades, numerous small …

Animal models for liver disease–a practical approach for translational research

YA Nevzorova, Z Boyer-Diaz, FJ Cubero… - Journal of …, 2020 - Elsevier
Animal models are crucial for improving our understanding of human pathogenesis,
enabling researchers to identify therapeutic targets and test novel drugs. In the current …

Western diet: implications for brain function and behavior

I López-Taboada, H González-Pardo… - Frontiers in …, 2020 - frontiersin.org
The Western diet (WD) pattern characterized by high daily intake of saturated fats and
refined carbohydrates often leads to obesity and overweight, and it has been linked to …

Of mice and men: models and mechanisms of diabetic cardiomyopathy

C Riehle, J Bauersachs - Basic research in cardiology, 2019 - Springer
Diabetes mellitus increases the risk of heart failure independent of co-existing hypertension
and coronary artery disease. Although several molecular mechanisms for the development …

Fructose impairs fat oxidation: Implications for the mechanism of western diet-induced NAFLD

MK Inci, SH Park, RN Helsley, SL Attia… - The Journal of nutritional …, 2023 - Elsevier
Increased fructose intake from sugar-sweetened beverages and highly processed sweets is
a well-recognized risk factor for the development of obesity and its complications. Fructose …

Diet high in linoleic acid dysregulates the intestinal endocannabinoid system and increases susceptibility to colitis in Mice

P Deol, P Ruegger, GD Logan, A Shawki, J Li… - Gut …, 2023 - Taylor & Francis
Inflammatory bowel disease (IBD) is a multifactorial disease with increasing incidence in the
US suggesting that environmental factors, including diet, are involved. It has been …