The ability to control cell volume is pivotal for cell function. Cell volume perturbation elicits a
wide array of signaling events, leading to protective (eg, cytoskeletal rearrangement) and …

The goal of contemporary research in pemphigus vulgaris and pemphigus foliaceus is to
achieve and maintain clinical remission without corticosteroids. Recent advances of …

Cell shrinkage is a hallmark and contributes to signaling of apoptosis. Apoptotic cell
shrinkage requires ion transport across the cell membrane involving K+ channels, Cl− or …

Purpose.: To determine whether hypertonic stress promotes increases in inflammatory
cytokine release through transient receptor potential vanilloid channel type 1 (TRPV1) …

Although it is accepted that pemphigus antibody binding to keratinocytes (KCs) evokes an
array of intracellular biochemical events resulting in cell detachment and death, the …

Male sex determination in mammals is induced by Sry, a gene whose regulation is poorly
understood. Here we show that mice mutant for the stress-response gene Gadd45g display …

The purpose of this article is to offer perspective on current understanding of ultraviolet (UV)
irradiation-induced signal transduction, with emphasis on membrane-initiated, non-nuclear …

Mammalian cells respond to environmental stress by activating a variety of protein kinases
critical for cellular signal transmission, such as the epidermal growth factor receptor (EGFR) …

Cell volume perturbation initiates a wide array of intracellular signalling cascades, leading to
protective and adaptive events and, in most cases, activation of volume‐regulatory osmolyte …

All known MAP kinase cascades have a simple three tier linear architecture; yet despite their
diverse range of inputs, they provide exquisitely precise and sensitive responses. Recent …