Methylation is a well‐known structural modification in organic and medicinal chemistry. This
review summarizes recent advances in methylation by categorizing specific methylation …

N-methylamine functionalities are valuable motifs, which play vital roles in the properties
and activities of essential fine and bulk chemicals including molecules used in life science …

Methanol is a fundamental feedstock and is widely used in the chemical and petroleum
industries. It can serve as a C1 source to make a variety of C–C and C–N bond formation …

An iron (0) complex bearing a cyclopentadienone ligand catalyzed N-methylation and N-
ethylation of aryl and aliphatic amines with methanol or ethanol in mild and basic conditions …

A general and mild strategy involving three-component carboarylation of unactivated
alkenes with protic C (sp3)–H feedstocks via photoredox catalysis was reported. This …

In the field of medicinal chemistry, the precise installation of a trideuteromethyl group is
gaining ever‐increasing attention. Site‐selective incorporation of the deuterated “magic …

Methanol is a potential hydrogen source and C1 synthon, which finds interesting
applications in both chemical synthesis and energy technologies. The effective utilization of …

α-Alkyl and α-olefin nitriles are very important for organic synthesis and medicinal chemistry.
However, different types of catalysts are employed to achieve either α-alkylation of nitriles by …

A general and chemoselective catalytic alkylation of nitriles using a homogeneous
nonprecious manganese catalyst is presented. This alkylation reaction uses naturally …

The construction of new C–C, C–N and C–O bonds by replacing hazardous and waste
generating chemicals with alcohols as the greener and sustainable reagents is one of the …