Critical overview of the use of Ru (II) polypyridyl complexes as photosensitizers in one-photon and two-photon photodynamic therapy

F Heinemann, J Karges, G Gasser - Accounts of chemical …, 2017 - ACS Publications
Conspectus Photodynamic Therapy (PDT) is an emerging technique to treat certain types of
cancer, bacterial, fungal, and viral infections, and skin diseases. In past years, different …

Ru (II) compounds: next-generation anticancer metallotherapeutics?

S Thota, DA Rodrigues, DC Crans… - Journal of medicinal …, 2018 - ACS Publications
Metal based therapeutics are a precious class of drugs in oncology research that include
examples of theranostic drugs, which are active in both diagnostic, specifically imaging, and …

Combination of light and Ru (II) polypyridyl complexes: Recent advances in the development of new anticancer drugs

L Conti, E Macedi, C Giorgi, B Valtancoli… - Coordination Chemistry …, 2022 - Elsevier
The increasing impact of cancer on worldwide mortality makes the research of novel
chemotherapeutic agents a current and challenging issue. In the recent years, transition …

Rationally designed ruthenium complexes for 1-and 2-photon photodynamic therapy

J Karges, S Kuang, F Maschietto, O Blacque… - Nature …, 2020 - nature.com
The use of photodynamic therapy (PDT) against cancer has received increasing attention
over recent years. However, the application of the currently approved photosensitizers (PSs) …

Antimicrobial photodynamic therapy: Latest developments with a focus on combinatory strategies

R Youf, M Müller, A Balasini, F Thétiot, M Müller… - Pharmaceutics, 2021 - mdpi.com
Antimicrobial photodynamic therapy (aPDT) has become a fundamental tool in modern
therapeutics, notably due to the expanding versatility of photosensitizers (PSs) and the …

The development of ruthenium (II) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications

FE Poynton, SA Bright, S Blasco, DC Williams… - Chemical Society …, 2017 - pubs.rsc.org
Ruthenium (II)[Ru (II)] polypyridyl complexes have been the focus of intense investigations
since work began exploring their supramolecular interactions with DNA. In recent years …

Two-photon-absorbing ruthenium complexes enable near infrared light-driven photocatalysis

G Han, G Li, J Huang, C Han, C Turro, Y Sun - Nature Communications, 2022 - nature.com
One-photon-absorbing photosensitizers are commonly used in homogeneous
photocatalysis which require the absorption of ultraviolet (UV)/visible light to populate the …

Molecular photosensitisers for two-photon photodynamic therapy

F Bolze, S Jenni, A Sour, V Heitz - Chemical Communications, 2017 - pubs.rsc.org
Two-photon excitation has attracted the attention of biologists, especially after the
development of two-photon excited microscopy in the nineties. Since then, new applications …

Design, photophysical properties, and applications of fluorene-based fluorophores in two-photon fluorescence bioimaging: A review

J Shaya, PR Corridon, B Al-Omari, A Aoudi… - … of Photochemistry and …, 2022 - Elsevier
Two-photon fluorescence microscopy (2PFM) emerged as a powerful alternative to
conventional one-photon microscopy. 2PFM typically uses two near-infrared (NIR) photons …

Ruthenium (II) polypyridyl complexes as mitochondria-targeted two-photon photodynamic anticancer agents

J Liu, Y Chen, G Li, P Zhang, C Jin, L Zeng, L Ji… - Biomaterials, 2015 - Elsevier
Clinical acceptance of photodynamic therapy is currently hindered by poor depth efficacy
and inefficient activation of the cell death machinery in cancer cells during treatment. To …