Comparative cellular analysis of motor cortex in human, marmoset and mouse
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally
conserved across mammals. Here, using high-throughput transcriptomic and epigenomic …
conserved across mammals. Here, using high-throughput transcriptomic and epigenomic …
Human neocortical expansion involves glutamatergic neuron diversification
The neocortex is disproportionately expanded in human compared with mouse,, both in its
total volume relative to subcortical structures and in the proportion occupied by …
total volume relative to subcortical structures and in the proportion occupied by …
[HTML][HTML] Neuronal types in the mouse amygdala and their transcriptional response to fear conditioning
The amygdala is a brain region primarily associated with emotional response. The use of
genetic markers and single-cell transcriptomics can provide insights into behavior …
genetic markers and single-cell transcriptomics can provide insights into behavior …
Pathophysiology and treatment of memory dysfunction after traumatic brain injury
R Paterno, KA Folweiler, AS Cohen - Current neurology and neuroscience …, 2017 - Springer
Memory is fundamental to everyday life, and cognitive impairments resulting from traumatic
brain injury (TBI) have devastating effects on TBI survivors. A contributing component to …
brain injury (TBI) have devastating effects on TBI survivors. A contributing component to …
Dendritic action potentials and computation in human layer 2/3 cortical neurons
A Gidon, TA Zolnik, P Fidzinski, F Bolduan, A Papoutsi… - Science, 2020 - science.org
The active electrical properties of dendrites shape neuronal input and output and are
fundamental to brain function. However, our knowledge of active dendrites has been almost …
fundamental to brain function. However, our knowledge of active dendrites has been almost …
[HTML][HTML] Shared and distinct transcriptomic cell types across neocortical areas
The neocortex contains a multitude of cell types that are segregated into layers and
functionally distinct areas. To investigate the diversity of cell types across the mouse …
functionally distinct areas. To investigate the diversity of cell types across the mouse …
Cerebellar modulation of the reward circuitry and social behavior
INTRODUCTION Although the cerebellum has long been considered to be a purely motor
structure, recent studies have revealed that it also has critical nonmotor functions. Cerebellar …
structure, recent studies have revealed that it also has critical nonmotor functions. Cerebellar …
Molecularly targetable cell types in mouse visual cortex have distinguishable prediction error responses
Predictive processing postulates the existence of prediction error neurons in cortex. Neurons
with both negative and positive prediction error response properties have been identified in …
with both negative and positive prediction error response properties have been identified in …
A suite of transgenic driver and reporter mouse lines with enhanced brain-cell-type targeting and functionality
Modern genetic approaches are powerful in providing access to diverse cell types in the
brain and facilitating the study of their function. Here, we report a large set of driver and …
brain and facilitating the study of their function. Here, we report a large set of driver and …
Advances in the automation of whole-cell patch clamp technology
Electrophysiology is the study of neural activity in the form of local field potentials, current
flow through ion channels, calcium spikes, back propagating action potentials and somatic …
flow through ion channels, calcium spikes, back propagating action potentials and somatic …