[HTML][HTML] Ketogenic diet for human diseases: the underlying mechanisms and potential for clinical implementations

H Zhu, D Bi, Y Zhang, C Kong, J Du, X Wu… - Signal transduction and …, 2022 - nature.com
The ketogenic diet (KD) is a high-fat, adequate-protein, and very-low-carbohydrate diet
regimen that mimics the metabolism of the fasting state to induce the production of ketone …

Efficacy and safety of low and very low carbohydrate diets for type 2 diabetes remission: systematic review and meta-analysis of published and unpublished …

JZ Goldenberg, A Day, GD Brinkworth, J Sato… - bmj, 2021 - bmj.com
Objective To determine the efficacy and safety of low carbohydrate diets (LCDs) and very
low carbohydrate diets (VLCDs) for people with type 2 diabetes. Design Systematic review …

Effect of a plant-based, low-fat diet versus an animal-based, ketogenic diet on ad libitum energy intake

KD Hall, J Guo, AB Courville, J Boring, R Brychta… - Nature medicine, 2021 - nature.com
The carbohydrate–insulin model of obesity posits that high-carbohydrate diets lead to
excess insulin secretion, thereby promoting fat accumulation and increasing energy intake …

[HTML][HTML] Ketogenic diets and chronic disease: weighing the benefits against the risks

L Crosby, B Davis, S Joshi, M Jardine, J Paul… - Frontiers in …, 2021 - frontiersin.org
Very-low-carbohydrate ketogenic diets have been long been used to reduce seizure
frequency and more recently have been promoted for a variety of health conditions …

[HTML][HTML] Review of current evidence and clinical recommendations on the effects of low-carbohydrate and very-low-carbohydrate (including ketogenic) diets for the …

CF Kirkpatrick, JP Bolick, PM Kris-Etherton… - Journal of clinical …, 2019 - Elsevier
Abstract Historically, low-carbohydrate (CHO) and very-low-CHO diets have been used for
weight loss. Recently, these diets have been promoted for type 2 diabetes (T2D) …

[HTML][HTML] Multi-dimensional roles of ketone bodies in fuel metabolism, signaling, and therapeutics

P Puchalska, PA Crawford - Cell metabolism, 2017 - cell.com
Ketone body metabolism is a central node in physiological homeostasis. In this review, we
discuss how ketones serve discrete fine-tuning metabolic roles that optimize organ and …

[HTML][HTML] Diets and drugs for weight loss and health in obesity–An update

J Aaseth, S Ellefsen, U Alehagen, TM Sundfør… - Biomedicine & …, 2021 - Elsevier
Numerous combinations of diets and pharmacological agents, including lifestyle changes,
have been launched to treat obesity. There are still ambiguities regarding the efficacies of …

[HTML][HTML] The burden of carbohydrates in health and disease

VJ Clemente-Suárez, J Mielgo-Ayuso… - Nutrients, 2022 - mdpi.com
Foods high in carbohydrates are an important part of a healthy diet, since they provide the
body with glucose to support bodily functions and physical activity. However, the abusive …

Scientific evidence of diets for weight loss: Different macronutrient composition, intermittent fasting, and popular diets

R Freire - Nutrition, 2020 - Elsevier
New dietary strategies have been created to treat overweight and obesity and have become
popular and widely adopted. Nonetheless, they are mainly based on personal impressions …

[HTML][HTML] Optimal diet strategies for weight loss and weight loss maintenance

JY Kim - Journal of obesity & metabolic syndrome, 2021 - ncbi.nlm.nih.gov
Obesity has become one of the most important public health problems worldwide, which
suggests the need for evidence-based dietary strategies for weight loss and its …