In this paper, we hypothesize that X chromosome‐associated mechanisms, which affect X‐
linked genes and are behind the immunological advantage of females, may also affect X …

Females as compared with males display better general health status, longevity, and
improved clinical course after injury and infection. It is generally believed that the female …

Background Chronic granulomatous disease (CGD) is a rare primary immunodeficiency
disorder of phagocytes resulting in impaired killing of bacteria and fungi. A mutation in one …

Females have a longer lifespan and better general health than males. Considerable number
of studies also demonstrated that, after trauma and sepsis, females present better outcomes …

Background: The flow cytometric dihydrorhodamine 123 (DHR) assay is used as a
screening test for chronic granulomatous disease (CGD), but complete myeloperoxidase …

Autoimmune diseases appear to have multiple contributing factors including genetics,
epigenetics, environmental factors, and aging. The predominance of females among …

Chronic granulomatous disease (CGD) is characterized by defects in the superoxide
producing enzyme NADPH oxidase causing phagocytes to improperly clear invading …

X-linked Granulomatous Disease (XL-CGD) carriers were previously thought to be clinically
healthy because random X-chromosome inactivation (XCI) allows approximately half of their …

Purpose Chronic granulomatous disease (CGD) is the most common phagocyte defect
disease. Here, we describe 114 CGD patients in our center and report a rare female infant …

Background: Chronic granulomatous disease (CGD) is a rare genetic disorder characterized
by failure of phagocytic leukocytes to destroy certain microbes. We present a study on CGD …