Viral infections can cause serious diseases for humans and animals. Accurate and early
detection of viruses is often crucial for clinical diagnosis and therapy. Aptamers are mostly …

Aptamers are molecular recognition elements made of nucleic acids. Diverse synthetic
aptamers have been discovered in a large number of SELEX experiments since 1990. This …

Aptamers are single-stranded nucleic acid sequences that can bind to target molecules with
high selectivity and affinity. Most aptamers are screened in vitro by a combinatorial biology …

Infectious diseases are a serious global problem, which not only take an enormous human
toll but also incur tremendous economic losses. In combating infectious diseases, rapid and …

Highly conserved noncoding RNA (ncRNA) elements in viral genomes and transcripts offer
new opportunities to expand the repertoire of drug targets for the development of …

Affinity reagents are essential tools in both basic and applied research; however, there is a
growing concern about the reproducibility of animal-derived monoclonal antibodies. The …

Salmonella is one of the most prevalent causing agents of food-and water-borne illnesses,
posing an ongoing public health threat. These food-poisoning bacteria contaminate the …

Aptamers are in vitro selected DNA or RNA molecules that are capable of binding a wide
range of nucleic and non-nucleic acid molecules with high affinity and specificity. They have …

An important current issue of modern molecular medicine and biotechnology is the search
for new approaches to early diagnostic assays and adequate therapy of infectious diseases …

Aptamers are often compared with antibodies since both types of molecules function as
targeting ligands for specific cancer cell recognition. However, aptamers offer several …