Nearly all genes presently mapped to chicken chromosome 16 (GGA 16) have either a
demonstrated role in immune responses or are considered to serve in immunity by reason of …

In comparison with the major histocompatibility complexes (MHCs) of typical mammals, the
chicken MHC is simple and compact with a single dominantly expressed class I molecule …

Expression of HLA-C varies widely across individuals in an allele-specific manner. This
variation in expression can influence efficacy of the immune response, as shown for …

Highly polymorphic major histocompatibility complex (MHC) molecules are at the heart of
adaptive immune responses, playing crucial roles in many kinds of disease and in …

Bovine leukemia virus (BLV) causes enzootic bovine leucosis, a malignant B-cell lymphoma
in cattle. The DNA sequence polymorphisms of bovine leukocyte antigen (BoLA)-DRB3 …

Structures of peptide-loaded major histocompatibility complex class I (pMHC-I) and class II
(pMHC-II) complexes are similar. However, whereas pMHC-II complexes include similar …

Abstract Background The duck (Anas platyrhynchos) is one of the principal natural hosts of
influenza A virus (IAV), harbors almost all subtypes of IAVs and resists to many IAVs which …

Chickens have played many roles in human societies over thousands of years, most recently
as an important model species for scientific discovery, particularly for embryology, virology …

In humans, killer immunoglobulin-like receptors (KIRs), expressed on natural killer (NK) and
thymus-derived (T) cells, and their ligands, primarily the classical class I molecules of the …

Like mammals, the major histocompatibility complex (MHC) of chickens is the primary
genetic locus for graft rejection, and encodes polymorphic classical class I and class II …