Antibacterial and antioxidant activities for natural and synthetic dual-active compounds
G Martelli, D Giacomini - European Journal of Medicinal Chemistry, 2018 - Elsevier
Antimicrobial resistance is widely recognized as a grave threat to global health in the 21st
century, since the past decades have seen a dramatic increase in human-pathogenic …
century, since the past decades have seen a dramatic increase in human-pathogenic …
Past, present and future of xanthine oxidase inhibitors: design strategies, structural and pharmacological insights, patents and clinical trials
Xanthine oxidase, a molybdo-flavoenzyme, and an isoform of xanthine dehydrogenase both
exist as xanthine oxidoreductase and are responsible for purine catabolism. Xanthine …
exist as xanthine oxidoreductase and are responsible for purine catabolism. Xanthine …
Antimicrobial and antitumor activity of S-methyl dithiocarbazate Schiff base zinc (II) complexes
F Ramilo-Gomes, Y Addis, I Tekamo, I Cavaco… - Journal of Inorganic …, 2021 - Elsevier
Schiff bases (SB) obtained from S-methyl dithiocarbazate and aromatic aldehydes:
salicylaldehyde (H 2 L 1), o-vanillin (H 2 L 2), pyridoxal (H 2 L 3) and 2, 6-diformyl-4 …
salicylaldehyde (H 2 L 1), o-vanillin (H 2 L 2), pyridoxal (H 2 L 3) and 2, 6-diformyl-4 …
Triple superphosphate modified by tin (II) chloride: As a reusable and efficient catalyst for the one-pot synthesis of xanthene and xanthenone derivatives under green …
A simple method was developed for preparing tin (II) chloride-triple superphosphate. The
material was thoroughly characterized using various techniques, including transform …
material was thoroughly characterized using various techniques, including transform …
'Lights, squaraines, action!'–the role of squaraine dyes in photodynamic therapy
E Lima, LV Reis - Future Medicinal Chemistry, 2022 - Taylor & Francis
Since they were first synthesized in 1965 by Treibs and Jacob, squaraine dyes have
revolutionized the polymethine dyes''universe'and their potential applications due to their …
revolutionized the polymethine dyes''universe'and their potential applications due to their …
Synthesis and in vitro evaluation of the antitumoral phototherapeutic potential of squaraine cyanine dyes derived from indolenine
E Lima, O Ferreira, VSD Gomes, AO Santos, RE Boto… - Dyes and …, 2019 - Elsevier
In this work several symmetrical indolenine squaraine dyes with different groups positioned
on the four-membered central ring, such as sulfur, barbituric acid, amino and methylamino …
on the four-membered central ring, such as sulfur, barbituric acid, amino and methylamino …
Therapeutic voyage of synthetic and natural xanthine oxidase inhibitors
N Agrawal, M Arya, P Kushwah - Chemical Biology & Drug …, 2023 - Wiley Online Library
Xanthine oxidase (XO) inhibitors are commonly used to treat gout, nephropathy, and renal
stone diseases related to hyperuricemia. However, recent research has shown that these …
stone diseases related to hyperuricemia. However, recent research has shown that these …
Synthetic heterocyclic derivatives as promising xanthine oxidase inhibitors: An overview
Inhibition of xanthine oxidase (XO) is an effective and most prominent therapeutic approach
for the management of gout. Discovery of its association in the pathophysiology of diabetes …
for the management of gout. Discovery of its association in the pathophysiology of diabetes …
Novel 3-[4-alkoxy-3-(1H-tetrazol-1-yl) phenyl]-1, 2, 4-oxadiazol-5 (4H)-ones as promising xanthine oxidase inhibitors: Design, synthesis and biological evaluation
J Gao, Z Zhang, B Zhang, Q Mao, X Dai, Q Zou… - Bioorganic …, 2020 - Elsevier
Xanthine oxidase (XO) is a critical target for the therapy of hyperuricemia and gout. In this
study, a number of 3-[4-alkoxy-3-(1 H-tetrazol-1-yl) phenyl]-1, 2, 4-oxadiazol-5 (4H)-ones (3a …
study, a number of 3-[4-alkoxy-3-(1 H-tetrazol-1-yl) phenyl]-1, 2, 4-oxadiazol-5 (4H)-ones (3a …
Melamine–Barbiturate Supramolecular Assembly as a pH‐Dependent Organic Radical Trap Material
VV Shilovskikh, AA Timralieva… - … A European Journal, 2020 - Wiley Online Library
In the last two decades, a large number of self‐assembled materials were synthesized and
they have already found their way into large‐scale industry and science. Hydrogen‐bond …
they have already found their way into large‐scale industry and science. Hydrogen‐bond …