Regulation of efferocytosis by caspase-dependent apoptotic cell death in atherosclerosis

A Tajbakhsh, PT Kovanen, M Rezaee, M Banach… - … International Journal of …, 2020 - Elsevier
During the growing process of the atherosclerotic lesions, lipid-filled macrophage foam cells
form, accumulate, and ultimately undergo apoptotic death. If the apoptotic foam cells are not …

Atherosclerosis: the culprit and co-victim of vascular dementia

YT Huang, FF Hong, SL Yang - Frontiers in neuroscience, 2021 - frontiersin.org
Vascular dementia (VD), a cerebrovascular disease which causes cognitive impairment, is
one of the significant factors that affects the quality of senectitude. Atherosclerosis (AS) is a …

Ursolic acid inhibits the cholesterol biosynthesis and alleviates high fat diet-induced hypercholesterolemia via irreversible inhibition of HMGCS1 in vivo

X Ma, Y Bai, K Liu, Y Han, J Zhang, Y Liu, X Hou… - Phytomedicine, 2022 - Elsevier
Background In hypercholesteremia, the concentrations of total cholesterol (TC) and low-
density lipoprotein cholesterol (LDL-C) are enhanced in serum, which is strongly associated …

Atorvastatin protects against cyclophosphamide-induced thyroid injury in rats via modulation of JNK/ERK/p38 MAPK signaling pathway

WY Abdelzaher, SA Abdel-Gaber, MA Fawzy… - International …, 2023 - Elsevier
Background Cancer chemotherapy is associated with various tissue toxicities that limit its
use. Cyclophosphamide (CYC) is one of the most commonly used antineoplastic and …

Electroacupuncture alleviated neuronal apoptosis following ischemic stroke in rats via midkine and ERK/JNK/p38 signaling pathway

Y Xing, SD Yang, MM Wang, F Dong, YS Feng… - Journal of Molecular …, 2018 - Springer
This study aimed to evaluate the effects of electroacupuncture (EA) intervention
administered at rats of middle cerebral artery occlusion (MCAO)/reperfusion. Fifty-four male …

Magnesium isoglycyrrhizinate promotes the activated hepatic stellate cells apoptosis via endoplasmic reticulum stress and ameliorates fibrogenesis in vitro and in vivo

M Bian, X Chen, C Zhang, H Jin, F Wang, J Shao… - Biofactors, 2017 - Wiley Online Library
Varied pathogenetic elements have been touched upon the liver fibrosis, including
inflammatory, stress, apoptosis and unfolded proteins aggregation. Magnesium …

[HTML][HTML] Effect of combined use of astragaloside IV (AsIV) and atorvastatin (AV) on expression of PPAR-γ and inflammation-associated cytokines in atherosclerosis rats

B Sun, R Rui, H Pan, L Zhang… - Medical science monitor …, 2018 - ncbi.nlm.nih.gov
Effect of Combined Use of Astragaloside IV (AsIV) and Atorvastatin (AV) on Expression of
PPAR-γ and Inflammation-Associated Cytokines in Atherosclerosis Rats - PMC Back to Top …

Targeting IL‐10, ZO‐1 gene expression and IL‐6/STAT‐3 trans‐signaling by a combination of atorvastatin and mesalazine to enhance anti‐inflammatory effects and …

NA El‐Mahdy, MES El‐Sayad… - Fundamental & …, 2021 - Wiley Online Library
Ulcerative colitis (UC) is a chronic inflammatory disease characterized by diffused
inflammation of the colon and rectum mucosa. The pathogenesis of UC is multifactorial, and …

1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea exerts neuro-protective effects against ischemic injury via suppressing JNK/p38 MAPK-mediated …

X Yi, D Fan, T Yi, H Chen, T Qing, Z Han… - Journal of Stroke and …, 2021 - Elsevier
Abstract Background 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU) is
a novel soluble epoxide hydrolase inhibitor which can protect against cerebral ischemic …

Taify Pomegranate Juice Extract Abrogates Testicular Dysfunction Induced by Acrylamide: Role of Inflammatory, Antioxidants, and Oxidative Stress Biomarkers

MM Soliman, SM Sayed, GBA Youssef, S Athobaiti… - Andrologia, 2023 - Wiley Online Library
High altitude (HA) poses various dangers to living organisms, the most serious of which are
oxidative stress and its accompanying metabolic problems, as well as hypoxia and its …