Scalable and accurate ECG simulation for reaction-diffusion models of the human heart

M Potse - Frontiers in physiology, 2018 - frontiersin.org
Realistic electrocardiogram (ECG) simulation with numerical models is important for
research linking cellular and molecular physiology to clinically observable signals, and …

Modelling and simulation for preclinical cardiac safety assessment of drugs with human iPSC-derived cardiomyocytes

P Kügler - Jahresbericht der Deutschen Mathematiker …, 2020 - Springer
As a potentially life threatening side effect, pharmaceutical compounds may trigger cardiac
arrhythmias by impeding the heart's electrical and mechanical function. For this reason, any …

Evaluation of a rapid anisotropic model for ECG simulation

S Pezzuto, P Kal'avský, M Potse, FW Prinzen… - Frontiers in …, 2017 - frontiersin.org
State-of-the-art cardiac electrophysiology models that are able to deliver physiologically
motivated activation maps and electrocardiograms (ECGs) can only be solved on high …

[HTML][HTML] Joint cardiac tissue conductivity and activation time estimation using confirmatory factor analysis

M Sun, NMS de Groot, RC Hendriks - Computers in Biology and Medicine, 2022 - Elsevier
Mathematical models of the electrophysiology of cardiac tissue play an important role when
studying heart rhythm disorders like atrial fibrillation. Model parameters such as conductivity …

Estimation of cardiac fibre direction based on activation maps

JW de Vries, M Sun, NMS de Groot… - ICASSP 2023-2023 …, 2023 - ieeexplore.ieee.org
Estimating tissue conductivity parameters from electrograms (EGMs) could be an important
tool for diagnosing and treating heart rhythm disorders such as atrial fibrillation (AF). One of …

[HTML][HTML] On complex dynamics in a Purkinje and a ventricular cardiac cell model

AH Erhardt, S Solem - … in Nonlinear Science and Numerical Simulation, 2021 - Elsevier
Cardiac muscle cells can exhibit complex patterns including irregular behaviour such as
chaos or (chaotic) early afterdepolarisations (EADs), which can lead to sudden cardiac …

[HTML][HTML] Cardiac tissue conductivity estimation using confirmatory factor analysis

M Sun, NMS de Groot, RC Hendriks - Computers in Biology and Medicine, 2021 - Elsevier
Impaired electrical conduction has been shown to play an important role in the development
of heart rhythm disorders. Being able to determine the conductivity is important to localize …

On the determination of ischemic regions in the monodomain model of cardiac electrophysiology from boundary measurements

E Beretta, C Cavaterra, L Ratti - Nonlinearity, 2020 - iopscience.iop.org
In this paper we consider the monodomain model of cardiac electrophysiology. After an
analysis of the well-posedness of the model we determine an asymptotic expansion of the …

[PDF][PDF] Local Impedance Characterization for Scar and Fibrosis Detection

MCM Antón - scholar.archive.org
Atrial fibrillation is a heart condition that causes an irregular and abnormally fast heart rate,
as well as a multifactorial and progressive cardiac disease with different manifestations in …

Virtual electrodes mechanisms predictions with a current-lifted monodomain model

Y Coudière, M Rioux - 2012 Computing in Cardiology, 2012 - ieeexplore.ieee.org
In this paper, we describe a monodomain model with a non-local source term that accounts
for any intra-or extracellular applied current, and specifically for the usual virtual electrode …