Brain injuries are devastating conditions, representing a global cause of mortality and
morbidity, with no effective treatment to date. Increased evidence supports the role of …

Epilepsy is a common chronic consequence of traumatic brain injury (TBI), contributing to
increased morbidity and mortality for survivors. As post-traumatic epilepsy (PTE) is drug …

Traumatic brain injury (TBI) is one of the most common pathological conditions impacting the
central nervous system (CNS). A neurological deficit associated with TBI results from a …

High-mobility group box-1 (HMGB1) is a nuclear protein associated with early inflammatory
changes upon extracellular secretion expressed in various cells, including neurons and …

Understanding the interplay between the innate immune system, neuroinflammation, and
epilepsy might offer a novel perspective in the quest of exploring new treatment strategies …

Traumatic brain injury (TBI) is a key contributor to global morbidity that lacks effective
treatments. Microbial infections are common in TBI patients, and their presence could modify …

The radiation fields in space define tangible risks to the health of astronauts, and significant
work in rodent models has clearly shown a variety of exposure paradigms to compromise …

Young children have a high risk of sustaining a traumatic brain injury (TBI), which can have
debilitating life-long consequences. Importantly, the young brain shows particular …

High mobility group box protein-1 (HMGB1) has been implicated as a key mediator of
neuroinflammation and neurodegeneration in a range of neurological conditions including …

Traumatic brain injury (TBI) is a leading cause of death and disability all over the world. TBI
leads to (1) an inflammatory response,(2) white matter injuries and (3) neurodegenerative …