Isoproterenol‐induced cardiac ischemia and fibrosis: Plant‐based approaches for intervention

P Allawadhi, A Khurana, N Sayed… - Phytotherapy …, 2018 - Wiley Online Library
Heart is the most active and incumbent organ of the body, which maintains blood flow, but
due to various pathological reasons, several acute and chronic cardiac complications arise …

Cardioprotective potential of plant-derived molecules: a scientific and medicinal approach

SMA Shah, M Akram, M Riaz, N Munir… - Dose …, 2019 - journals.sagepub.com
Since the beginning of human civilization, plants have been used in alleviating the human
distress and it was recorded for about thousands of years ago that the plants are being used …

Molecular understanding of the protective role of natural products on isoproterenol-induced myocardial infarction: A review

ZW Wong, PV Thanikachalam… - Biomedicine & …, 2017 - Elsevier
Modern medicine has been used to treat myocardial infarction, a subset of cardiovascular
diseases, and have been relatively effective but not without adverse effects. Consequently …

[HTML][HTML] Indole-based small molecules as potential therapeutic agents for the treatment of fibrosis

R Qin, Q Zhao, B Han, HP Zhu, C Peng… - Frontiers in …, 2022 - frontiersin.org
Indole alkaloids are widely distributed in nature and have been particularly studied because
of their diverse biological activities, such as anti-inflammatory, anti-tumor, anti-bacterial, and …

Ablation of the stress protease OMA1 protects against heart failure in mice

R Acin-Perez, AV Lechuga-Vieco… - Science Translational …, 2018 - science.org
Heart failure (HF) is a major health and economic burden in developed countries. It has
been proposed that the pathogenesis of HF may involve the action of mitochondria. We …

[HTML][HTML] Preventive effect of Agnucastoside C against Isoproterenol-induced myocardial injury

S Panda, A Kar, S Biswas - Scientific reports, 2017 - nature.com
An iridoid glycoside, agnucastoside C (ACC) was isolated from the leaves of Moringa
oliefera and its cardio protective potential was investigated in adult rats by examining the …

Chlorogenic acid ameliorates isoproterenol-induced myocardial injury in rats by stabilizing mitochondrial and lysosomal enzymes

P Akila, L Asaikumar, L Vennila - Biomedicine & Pharmacotherapy, 2017 - Elsevier
This study was deliberated to aspire the effects of chlorogenic acid (CGA) against
myocardial infarction (MI) induced by Isoproterenol (ISO), in a rat model. In the pathology of …

The protective role of lutein on isoproterenol-induced cardiac failure rat model through improving cardiac morphology, antioxidant status via positively regulating Nrf2 …

B Ouyang, Z Li, X Ji, J Huang, H Zhang… - Pharmaceutical …, 2019 - Taylor & Francis
Context: Lutein (LU) is a major carotenoid with various pharmacological activities including
anti-inflammatory, antioxidant and anti-apoptosis. Objective: The cardioprotective efficacy of …

Fuziline alleviates isoproterenol‐induced myocardial injury by inhibiting ROS‐triggered endoplasmic reticulum stress via PERK/eIF2α/ATF4/Chop pathway

C Fan, Z Yao, M Ye, L Fu, G Zhu… - Journal of Cellular and …, 2020 - Wiley Online Library
Fuziline, an aminoalcohol‐diterpenoid alkaloid derived from Aconiti lateralis radix preparata,
has been reported to have a cardioprotective activity in vitro. However, the potential …

Anethole's effects against myocardial infarction: The role of TLR4/NFκB and Nrf2/HO1 pathways

NS Younis, ME Mohamed - Chemico-Biological Interactions, 2022 - Elsevier
Background Exploring new drugs for the management of myocardial infarction (MI) is crucial,
as MI is a major contributor to mortality worldwide. Anethole, a naturally occurring essential …