Targeting the signaling in Epstein–Barr virus-associated diseases: Mechanism, regulation, and clinical study
Y Cao, L Xie, F Shi, M Tang, Y Li, J Hu, L Zhao… - Signal transduction and …, 2021 - nature.com
Epstein–Barr virus-associated diseases are important global health concerns. As a group I
carcinogen, EBV accounts for 1.5% of human malignances, including both epithelial-and …
carcinogen, EBV accounts for 1.5% of human malignances, including both epithelial-and …
Novel therapeutics for Epstein–Barr virus
G Andrei, E Trompet, R Snoeck - Molecules, 2019 - mdpi.com
Epstein–Barr virus (EBV) is a human γ-herpesvirus that infects up to 95% of the adult
population. Primary EBV infection usually occurs during childhood and is generally …
population. Primary EBV infection usually occurs during childhood and is generally …
Antiviral drugs for EBV
JS Pagano, CB Whitehurst, G Andrei - Cancers, 2018 - mdpi.com
Epstein–Barr virus (EBV) infects up to 95% of the adult human population, with primary
infection typically occurring during childhood and usually asymptomatic. However, EBV can …
infection typically occurring during childhood and usually asymptomatic. However, EBV can …
[HTML][HTML] Unexpected patterns of Epstein–Barr virus transcription revealed by a high throughput PCR array for absolute quantification of viral mRNA
RJ Tierney, CD Shannon-Lowe, L Fitzsimmons, AI Bell… - Virology, 2015 - Elsevier
We have validated a flexible, high-throughput and relatively inexpensive RT-QPCR array
platform for absolute quantification of Epstein–Barr virus transcripts in different latent and …
platform for absolute quantification of Epstein–Barr virus transcripts in different latent and …
Suppression of Epstein-Barr virus DNA load in latently infected nasopharyngeal carcinoma cells by CRISPR/Cas9
KS Yuen, ZM Wang, NHM Wong, ZQ Zhang, TF Cheng… - Virus research, 2018 - Elsevier
Epstein-Barr virus (EBV) infects more than 90% of the world's adult population. Once
established, latent infection of nasopharyngeal epithelial cells with EBV is difficult to …
established, latent infection of nasopharyngeal epithelial cells with EBV is difficult to …
Therapies based on targeting Epstein‐Barr virus lytic replication for EBV‐associated malignancies
H Li, J Hu, X Luo, AM Bode, Z Dong, Y Cao - Cancer Science, 2018 - Wiley Online Library
In recent years, Epstein‐Barr virus (EBV) lytic infection has been shown to significantly
contribute to carcinogenesis. Thus, therapies aimed at targeting the EBV lytic cycle have …
contribute to carcinogenesis. Thus, therapies aimed at targeting the EBV lytic cycle have …
Knockout of Epstein-Barr virus BPLF1 retards B-cell transformation and lymphoma formation in humanized mice
CB Whitehurst, G Li, SA Montgomery, ND Montgomery… - MBio, 2015 - Am Soc Microbiol
ABSTRACT BPLF1 of Epstein-Barr virus (EBV) is classified as a late lytic cycle protein but is
also found in the viral tegument, suggesting its potential involvement at both initial and late …
also found in the viral tegument, suggesting its potential involvement at both initial and late …
Management of Cytomegalovirus Infections in the Era of the Novel Antiviral Players, Letermovir and Maribavir
Cytomegalovirus (CMV) infections may increase morbidity and mortality in
immunocompromised patients. Until recently, standard antiviral drugs against CMV were …
immunocompromised patients. Until recently, standard antiviral drugs against CMV were …
Spectrum of activity and mechanisms of resistance of various nucleoside derivatives against gammaherpesviruses
N Coen, S Duraffour, D Topalis… - Antimicrobial Agents …, 2014 - Am Soc Microbiol
The susceptibilities of gammaherpesviruses, including Epstein-Barr virus (EBV), Kaposi's
sarcoma-associated herpesvirus (KSHV), and animal rhadinoviruses, to various nucleoside …
sarcoma-associated herpesvirus (KSHV), and animal rhadinoviruses, to various nucleoside …
The lytic phase of Epstein–Barr virus plays an important role in tumorigenesis
Y Liang, Y Zhang, B Luo - Virus Genes, 2023 - Springer
Epstein–Barr virus (EBV) is a recognized oncogenic virus that is related to the occurrence of
lymphoma, nasopharyngeal carcinoma (NPC), and approximately 10% of gastric cancer …
lymphoma, nasopharyngeal carcinoma (NPC), and approximately 10% of gastric cancer …